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Fig. 8 | Journal of Ovarian Research

Fig. 8

From: MicroRNA-424/503 cluster members regulate bovine granulosa cell proliferation and cell cycle progression by targeting SMAD7 gene through activin signalling pathway

Fig. 8

Dose-dependent activin A treatment increased bovine granulosa cell proliferation, reduced the SMAD7 and miR-424/503 expression levels. Cell proliferation assay (a) after dose-dependent Activin A treatment (Activin A: 25 ng/mL, 50 ng/mL and 100 ng/mL). The relative expression levels of PCNA (b), STAR (c), SMAD7 (e), ACVR2A (f), miR-424 (g) and miR-503 (h) in granulosa cells treated Activin A. The protein expression of STAR in granulosa cells treated with treated Activin A (d). The bar graphs indicate the mean ± SEM (**p < 0.01, ***p < 0.001). Numbers above western blots represent relative protein density

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Journal of Ovarian Research

ISSN: 1757-2215

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