Fig. 2From: Consanguineous familial study revealed biallelic FIGLA mutation associated with premature ovarian insufficiency(a) In silico analysis of the alternative start site and potential resulting protein. The MutationTaster online prediction tool (http://www.mutationtaster.org/) was used in the current analysis. The predicted results for c.2 T > C showed that the start ATG shifted, the Kozak consensus sequence changed, and the entire protein amino acid sequence frameshifted and was changed. The green box indicates the wild-type amino acid sequence, while the red box indicates the mutated amino acid sequence. (b) and (c) The wild-type (b) and mutated (c) sequences of FIGLA. The light grown indicate the putative translated protein sequencesBack to article page