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Table 4 Patient history and presence of PD-1 and PD-L1

From: Stratification of ovarian tumor pathology by expression of programmed cell death-1 (PD-1) and PD-ligand- 1 (PD-L1) in ovarian cancer

   combined PD-1a PD-L1
  No. Patients n (%) p-value n (%) P-value
Age at diagnosis      
 <  60 27 24 (88.9) 0.99 9 (33.3) 0.93
 ≥ 60 28 24 (85.7) 9 (32.1)
Stage of cancer      
 I-II 9 9 (100.0) 0.58 5 (55.6) 0.13
 III-IV 46 39 (84.8) 13 (28.3)
Tumor grade      
 1–2 13 12 (92.3) 0.99 1 (7.7) 0.040
 3 41 35 (85.4) 17 (41.5)
  1. aThe presence of PD-1 in the tumor epithelial or stromal compartment (combined PD-1), and PD-L1 was defined as the occurrence of these molecules (scores 1, 2, 3, or 4) in tissue sections. Tumor grade was unknown for one patient. Significant P-values are indicated in italics