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Table 4 Patient history and presence of PD-1 and PD-L1

From: Stratification of ovarian tumor pathology by expression of programmed cell death-1 (PD-1) and PD-ligand- 1 (PD-L1) in ovarian cancer

  

combined PD-1a

PD-L1

 

No. Patients

n (%)

p-value

n (%)

P-value

Age at diagnosis

     

 <  60

27

24 (88.9)

0.99

9 (33.3)

0.93

 ≥ 60

28

24 (85.7)

9 (32.1)

Stage of cancer

     

 I-II

9

9 (100.0)

0.58

5 (55.6)

0.13

 III-IV

46

39 (84.8)

13 (28.3)

Tumor grade

     

 1–2

13

12 (92.3)

0.99

1 (7.7)

0.040

 3

41

35 (85.4)

17 (41.5)

  1. aThe presence of PD-1 in the tumor epithelial or stromal compartment (combined PD-1), and PD-L1 was defined as the occurrence of these molecules (scores 1, 2, 3, or 4) in tissue sections. Tumor grade was unknown for one patient. Significant P-values are indicated in italics