Table 3 Median percentage changes in the investigated markers of ovarian reserve 3 months after supracervical hysterectomy, uterine artery embolization or after a course of UPA therapy
Variable | Study group | Percentage change at 3-month follow-up | P | Post-hoc analysis |
|---|---|---|---|---|
AFC | Hysterectomy | −8.4 (− 15 – − 4.2) | < 0.001 | Hysterectomy vs UPA: NS |
UPA | −7.8 (−14.3–0) | Hysterectomy vs UAE: p < 0.001 | ||
UAE | − 63.4 (− 78.9 – − 37.5) | UPA vs UAE: p < 0.001 | ||
AMH | Hysterectomy | −3.5 (− 10–4.8) | < 0.001 | Hysterectomy vs UPA: NS |
UPA | −5.8 (− 7.7 – − 5.1) | Hysterectomy vs UAE: p < 0.001 | ||
UAE | − 61.9 (− 82 – − 47.4) | UPA vs UAE: p < 0.001 | ||
INH | Hysterectomy | −7.4 (−15.1 – − 2.5) | < 0.001 | Hysterectomy vs UPA: NS |
UPA | − 7.0 (− 10.6–3.0) | Hysterectomy vs UAE: p < 0.001 | ||
UAE | −60.7 (− 74.5 – − 51.2) | UPA vs UAE: p < 0.001 | ||
FSH | Hysterectomy | 21.5 (−9.1–35) | < 0.001 | Hysterectomy vs UPA: NS |
UPA | 12.7 (− 9.8–27) | Hysterectomy vs UAE: p < 0.001 | ||
UAE | 125.6 (51–295.8) | UPA vs UAE: p < 0.001 | ||
E2 | Hysterectomy | −13.3 (− 19.5 – − 3.5) | < 0.001 | Hysterectomy vs UPA: NS |
UPA | −3.3 (− 10.3–11.4) | Hysterectomy vs UAE: p < 0.001 | ||
UAE | −41 (−53.5–7.6) | UPA vs UAE: p < 0.001 |