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Fig. 1 | Journal of Ovarian Research

Fig. 1

From: Wounding promotes ovarian cancer progression and decreases efficacy of cisplatin in a syngeneic mouse model

Fig. 1

Bioluminescent luciferase activity and sensitivity to cisplatin of ID8-L11 and ID8-L15 cells in vitro. a Concentration-dependent bioluminesence imaging of both cell sublines compared to non-luciferase expressing parental ID8 cells. Different concentrations of cells were added to a 96-well tissue culture plate and imaged on an IVIS Spectrum In Vivo Imaging System. b Graphical representation of the quantitation of images shown in Panel A (dashed lines). Solid lines indicate a linear fitting of the data. c-e Response of cells to cisplatin. Parental ID8 (c), ID8-L11 (d), or ID8-L15 (e) cells were seeded into 96 well plates. One day later, cells were treated with 0, 10, 25, or 50 μM cisplatin and relative cell viability was determined by a XTT dye-reduction assay. Points represent the mean ± SEM of 8 determinations. Within each time point, points with different letters are statistically different from one another as determined by ANOVA followed by SNK multiple comparison test (p < 0.05)

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