Fig. 3From: Use of a Small Animal Radiation Research Platform (SARRP) facilitates analysis of systemic versus targeted radiation effects in the mouse ovaryTBI and targeted radiation to the ovary with X-rays at a dose of 1 Gy cause significant follicle loss. a Follicle classes were defined according to morphological criteria. Primordial follicles were identified as an oocyte surrounded by squamous granulosa cells. Primary follicles were defined as an oocyte surrounded by one layer of cuboidal granulosa cells. Secondary follicles were defined as an oocyte surrounded by two or more layers of cuboidal granulosa cells. Antral follicles were defined as an oocyte surrounded by multiple layers of cuboidal cells with an antral space filled with follicular fluid forming in the middle of the follicle. Growing follicles were considered to be follicles at the primary stage or beyond. The average number of (b) primordial follicles per section and (c) growing follicles per section were quantified in ovaries from each cohort (Sham, TBI, and T2). A one-way ANOVA was performed between cohorts, and statistical significance was defined as *p < 0.05. The scale bar is 50 μmBack to article page