Fig. 6

Targeted radiation to a single ovary causes significant damage to the targeted ovary without having off target effects on the contralateral ovary. The average number of (a) primordial follicles per section and (b) growing follicles per section were quantified in both the non-targeted and targeted ovaries. These data were delineated by individual animal (letter) (c-d). In (e-f), the same data that are shown in (a-b) were plotted alongside the average follicle counts for the Sham cohort shown in Fig. 3b-c. The data were analyzed either by unpaired t-tests or one-way ANOVAS. Statistical significance was defined as *p < 0.05