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Fig. 7 | Journal of Ovarian Research

Fig. 7

From: Gonadotropin and steroid hormones regulate pluripotent very small embryonic-like stem cells in adult mouse uterine endometrium

Fig. 7

PCNA expression in endometrial sections after follicle stimulating hormone treatment to bilaterally ovariectomized mice. a, b. PCNA expression after FSH treatment was similar to after E treatment in the epithelial cells implying few cells were positive and few were negative for PCNA. c, d, e, f.  At higher magnification one could observe the small spherical cells expressing PCNA (black arrow) and these cells were also evidently dividing (red arrow). It is interesting to note that mitotic figures are not observed in the epithelial cells. Note two clump of cells (broken circle) in the basal region possibly suggestive of clonal expansion of stem cells. This becomes very clear on studying stem cell smears (Fig. 12). Scale bar 20 μm

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