Fig. 8

OCT-4 expression after E (a, b) and P (c, d, e) treatment to bilaterally ovariectomized mice. OCT-4 expression was primarily in the cytoplasm of epithelial cells after E and P treatment. Few spherical cells expressing nuclear OCT-4A were also visualized (arrow). Endothelial cells lining the blood vessels (BV) also expressed cytoplasmic OCT-4. Scale bar 20 μm