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Table 1 Comparison of the general characteristics of patients with and without elevated FF-FGF13

From: Intrafollicular fibroblast growth factor 13 in polycystic ovary syndrome: relationship with androgen levels and oocyte developmental competence

Characteristics

Elevated FF-FGF13

 

Yes

No

P values

FF-FGF13 (pg/mL)

143.22 (119.11–190.27)

70.03 (53.20–86.94)

n

19

56

Age (years)

28.0 (23.0–33.0)

27.0 (25.0–30.0)

0.69

BMI (kg/m2)

22.6 (20.2–24.0)

20.3 (19.0–23.5)

0.06

PCOS, n (%)

14 (73.7)

29 (51.8)

0.095

Increased ovarian volume, n (%)

13 (68.2)

21 (38.9)

0.021

FF-LH (IU/L)

2.73 (0.33–4.33)

0.94 (0.29–4.460)

0.57

FF-FSH (IU/L)

4.57 (3.50–6.78)

4.49 (3.36–5.55)

0.72

FF-TT (nmol/L)

51.90 (22.18–88.52)

24.71(16.32–43.44)

0.016

FF-FAI

1.86 (0.99–2.72)

0.95 (0.65–1.31)

0.014

FF-E2 (μg/L)

2028.00 (1218.00–3400.00)

1685.00 (1344.00–2353.00)

0.65

FF-P4 (mg/L)

27.62 (16.70–58.70)

39.88 (22.93–56.21)

0.21

FF-IL-6 (pg/mL)

5.39 (4.69–7.96)

5.74 (4.92–9.95)

0.71

FF-FGF21 (pg/mL)

16.48 (13.47–24.50)

13.97 (9.47–17.98)

0.023

  1. Data are given as the median (interquartile range) for skewed variables or as the number (proportion) for categorical variables. “Elevated” FF-FGF13 levels were defined as follicular levels in the upper quartile (i.e., ≥117.51 pg/mL). P values were accessed using Kruskal-Wallis tests (continuous variables) and χ2 tests (categorical variables). FGF13 fibroblast growth factor 13; BMI body mass index; PCOS polycystic ovary syndrome; FF follicular fluid; LH luteinizing hormone; FSH follicle-stimulating hormone; TT total testosterone; FAI free androgen index; E2: estradiol; P4: progesterone; IL6: interleukin-6; FGF21: fibroblast growth factor 21