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Fig. 3 | Journal of Ovarian Research

Fig. 3

From: Exosomal miR-1290 is a potential biomarker of high-grade serous ovarian carcinoma and can discriminate patients from those with malignancies of other histological types

Fig. 3

Serum miR-1290 expression reflects HGSOC tumor burden. (a) Relative serum miR-1290 expression levels between HGSOC patients at early (I + II) (n = 8) and advanced (III + IV) stage (n = 22) are shown. The average miR-1290 expression level in healthy controls (n = 13) was normalized to 1.0. The box-and-whisker plots indicate the median and interquartile range. (b) Relative miR-1290 expression levels in matched serum samples from HGSOC patients before and after primary debulking surgery (PDS). Individual changes in the serum expression of miR-1290 in HGSOC patients before and after PDS are shown. The average miR-1290 expression level in healthy controls (n = 13) was normalized to 1.0. **, P < 0.01; n.s., not significant

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