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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: Exosomal miR-1290 is a potential biomarker of high-grade serous ovarian carcinoma and can discriminate patients from those with malignancies of other histological types

Fig. 4

Diagnostic performance of miR-1290 for the discrimination of HGSOC from non-HGSOC. (a) Relative miR-1290 expression levels in sera from HGSOC patients (n = 30) and patients with EOC other than HGSOC (n = 40). The average miR-1290 expression level in healthy controls (n = 13) was normalized to 1.0. The box-and-whisker plots indicate the median and interquartile range. (b) CA125 expression levels in sera from HGSOC patients (n = 30) and patients with EOC other than HGSOC (n = 40). The box-and-whisker plots indicate the median and interquartile range. (c) ROC curves for the identification of HGSOC patients from patients with EOC other than HGSOC (n = 40) based on the expression of CA125 (gray line), miR-1290 (black line), and the combination of both (dotted line). **, P < 0.01; n.s., not significant

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