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Table 2 Drug-resistance markers in OC identified by MS-based proteomic techniques

From: Mass spectrometry-based proteomics techniques and their application in ovarian cancer research

Chemoresistance markers

MS technique

Ref.

Annexin 3;

Destrin;

Cofilin1;

Gluthathione-S transferase omega 1;

Cytosolic NADP+ dependent isocitrate dehydrogenase

MALDI-TOF

[87]

ATP synthase subunit alpha;

Peroxiredoxin 3;

Prohibitin;

Electron transfer flavoprotein subunit alpha;

Aldehyde dehydrogenase X

MALDI-TOF

[88]

ERp57

MALDI-TOF

ESI-Q-TOF

[89]

Tumor rejection antigen (gp96) 1;

Triose phosphate isomerase;

Palmitoyl-protein thioesterase1 precursor;

ER-associated DNAJ

MALDI-TOF

ESI-Q-TOF

[91]

Aldehyde dehydrogenase 1 family, member A1;

Annexin A1;

Heterogeneous Nuclear Ribonucleoproteins A2;

Rho GDP dissociation inhibitor

MALDI-TOF

LC-MS/MS

[90]

Activated leukocyte cell adhesion molecule;

A kinase anchoring protein 12;

Nestin

Orbitrap

[92]

Thioredoxin domain containing 17

Orbitrap

[93]

Mitochondrial topoisomerase I

Orbitrap

[94]

Cell recognition molecule CASPR3;

S100 protein family members;

Junction adhesion molecule Claudin 4;

CDC42-binding protein kinase beta

ESI-MS/MS

[95]

P53 binding protein 1;

Catenin delta 1 and plakoglobin;

EGF-containing fibulin-like extracellular matrix protein 1;

Voltage-dependent anion-selective channel protein 1

HPLC-ESI-MS/MS

[96]

Pyruvate kinase isozymes M1/M2;

Heat Shock Protein Family D

ESI-Q-TOF

[97]