Fig. 7From: Luteolin sensitizes the antitumor effect of cisplatin in drug-resistant ovarian cancer via induction of apoptosis and inhibition of cell migration and invasionLuteolin in combination with cisplatin enhanced apoptosis in vivo. Apoptosis of tumor sections were detected by TUNEL assay. a Representative images of apoptotic cells in each group (apoptotic cells in green and the cell nuclei in blue). b The tumor cell apoptosis rates of 8 groups were analyzed. * P < 0.05, ** P < 0.01, vs. control; # P < 0.05 vs. cisplatin. CDDP: cisplatin. CDDP combined with luteolin (20 mg, 40 mg) exhibited a synergistic effect on the apoptosis induction of xenograft tumor (Q = 1.73 ± 0.03 and 2.95 ± 0.16, respectively, > 1, P < 0.01 and P < 0.01, respectively)Back to article page