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Table 2 Ovarian stimulation characteristics and outcomes of patients with different pre-ovulatory E2 level patterns

From: Decrease in preovulatory serum estradiol is a valuable marker for predicting premature ovulation in natural/unstimulated in vitro fertilization cycle

Characteristics

E2(ng/mL)

P Value

Group A(> 10% increase)

(n = 403)

Group B(±10% plateau)

(n = 192)

Group C (> 10% decrease)

(n = 206)

No premature LH surge (HCG/Tiplilin trigger)

282(69.98%)

108(56.25%)

96(46.60%)

a

Premature LH surge

121(30.02%)

84(43.75%)

110(53.40%)

a

Pre-ovulatory P level

0.3 ± 0.48

0.5 ± 0.45

0.5 ± 0.33

NS

Number of oocytes retrieved

0.80 ± 0.496

0.76 ± 0.68

0.64 ± 0.55

b

Oocyte retrieval rate

75.99 ± 40.47

77.31 ± 38.64

77.28 ± 39.09

NS

Mature oocytes

0.70 ± 0.51

0.67 ± 0.67

0.55 ± 0.54

b

Mature oocytes rate (%)

89.00 ± 1.73

89.98 ± 2.75

87.70 ± 2.93

NS

Normal fertilization rate

89.62 ± 30.27

88.57 ± 31.11

84.82 ± 35.41

NS

Embryos frozen

0.40 ± 0.51

0.35 ± 0.51

0.27 ± 0.45

c

Top-quality embryos

0.32 ± 0.49

0.22 ± 0.43

0.16 ± 0.37

c

Premature ovulation

19(4.71%)

24(12.37%))

63(30.58%)

P < 0.001

IVF cycles without embryo frozen

241(59.8%)

122(63.5%)

142(68.9%)

c

  1. Data are presented as the means ±SD. a indicates group A versus group B, C; b indicates group C versus group A, B; c indicates group C versus group A;