Fig. 2
From: Overexpression of CCDC69 activates p14ARF/MDM2/p53 pathway and confers cisplatin sensitivity
CCDC69 confers chemo-sensitivity in 293 and A2780 cells. a. Sensitization of cells to cisplatin after CCDC69 overexpression as revealed by the CCK-8 cytotoxicity assay. b. Apoptosis was analyzed by flow cytometry after annexin V and propidium iodide staining. Total apoptosis is the sum of the percentage of annexin V only and annexin V/propidium iodide stained cells. c. immunoblot analysis of CCDC69 and cleaved PARP in 293 cells after stable CCDC69 overexpression and treatments with cisplatin for 48 h. Loading control, GAPDH
