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Table 3 Cut-off values and univariate analysis of PET metabolic parameters for prediction of suboptimal cytoreduction

From: The ability of whole-body SUVmax in F-18 FDG PET/CT to predict suboptimal cytoreduction during primary debulking surgery for advanced ovarian cancer

 

Median (range)

Cut-off value

AUC

P value

OR

95% CI

P value

Predictive score

PET 0

3.5 (0.0–16.0)

>  2.2

0.670

0.0277

5.250

1.41–19.59

0.0136

5

PET 1

4.0 (0.0–14.3)

>  7.9

0.657

0.0563

4.148

1.13–15.19

0.0317

4

PET 2

4.5 (0.0–23.0)

> 5.3

0.529

0.7387

0.440

0.12–1.63

0.2196

 

PET 3

3.8 (0.0–18.2)

>  0

0.652

0.0546

5.921

1.17–30.02

0.0318

6

PET 4

2.9 (0.0–19.0)

>  1.8

0.593

0.2599

2.889

0.78–10.68

0.1118

 

PET 5

4.9 (0.0–18.0)

>  4.3

0.500

1.000

0.553

0.17–1.80

0.3244

 

PET 6

10.0 (0.0–24.2)

>  6.7

0.510

0.9097

0.393

0.10–1.48

0.1683

 

PET 7

6.1 (0.0–13.2)

>  4.5

0.506

0.9450

0.425

0.13–1.40

0.1599

 

PET 8

5.7 (0.0–16.8)

>  6

0.631

0.1224

1.118

0.97–1.29

0.1180

 

WB1SUVmax

46.4 (7.4–134.0)

>  68.8

0.621

0.1644

3.429

0.97–12.14

0.0561

 

WB2SUVmax

53.3 (7.4–153.0)

>  76.2

0.621

0.1957

4.148

1.13–15.19

0.0317

4

PCI

22.0 (7.0–32.0)

>  10

0.562

0.4448

5.760

0.66–49.91

0.1120

 

Age

58.0 (37–74)

≥ 60

0.500

1.000

1.000

0.30–3.26

1.0000

 

Ascites

NA

> 500

0.515

0.8173

0.842

0.21–3.40

0.8107

 

Ca 125

573.7 (38–6000)

> 1881

0.568

0.4595

2.133

0.62–7.39

0.2221

 

ECOG PS

NA

≥2

0.618

0.0746

4.091

0.97–17.29

0.0520

4

Stage

NA

IV

0.603

0.1464

2.70

0.75–9.66

0.1265

 
  1. PET Positron emission tomography, WB1SUVmax Whole-body 1 standardized uptake value, WB2SUVmax Whole-body 2 standardized uptake value, PCI Peritoneal cancer index, ECOG PS Eastern cooperative oncology group performance status, NA Not available, AUC Area under the curve, OR Odds ratio, 95% CI 95% confidence interval