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Table 3 Cut-off values and univariate analysis of PET metabolic parameters for prediction of suboptimal cytoreduction

From: The ability of whole-body SUVmax in F-18 FDG PET/CT to predict suboptimal cytoreduction during primary debulking surgery for advanced ovarian cancer

  Median (range) Cut-off value AUC P value OR 95% CI P value Predictive score
PET 0 3.5 (0.0–16.0) >  2.2 0.670 0.0277 5.250 1.41–19.59 0.0136 5
PET 1 4.0 (0.0–14.3) >  7.9 0.657 0.0563 4.148 1.13–15.19 0.0317 4
PET 2 4.5 (0.0–23.0) > 5.3 0.529 0.7387 0.440 0.12–1.63 0.2196  
PET 3 3.8 (0.0–18.2) >  0 0.652 0.0546 5.921 1.17–30.02 0.0318 6
PET 4 2.9 (0.0–19.0) >  1.8 0.593 0.2599 2.889 0.78–10.68 0.1118  
PET 5 4.9 (0.0–18.0) >  4.3 0.500 1.000 0.553 0.17–1.80 0.3244  
PET 6 10.0 (0.0–24.2) >  6.7 0.510 0.9097 0.393 0.10–1.48 0.1683  
PET 7 6.1 (0.0–13.2) >  4.5 0.506 0.9450 0.425 0.13–1.40 0.1599  
PET 8 5.7 (0.0–16.8) >  6 0.631 0.1224 1.118 0.97–1.29 0.1180  
WB1SUVmax 46.4 (7.4–134.0) >  68.8 0.621 0.1644 3.429 0.97–12.14 0.0561  
WB2SUVmax 53.3 (7.4–153.0) >  76.2 0.621 0.1957 4.148 1.13–15.19 0.0317 4
PCI 22.0 (7.0–32.0) >  10 0.562 0.4448 5.760 0.66–49.91 0.1120  
Age 58.0 (37–74) ≥ 60 0.500 1.000 1.000 0.30–3.26 1.0000  
Ascites NA > 500 0.515 0.8173 0.842 0.21–3.40 0.8107  
Ca 125 573.7 (38–6000) > 1881 0.568 0.4595 2.133 0.62–7.39 0.2221  
ECOG PS NA ≥2 0.618 0.0746 4.091 0.97–17.29 0.0520 4
Stage NA IV 0.603 0.1464 2.70 0.75–9.66 0.1265  
  1. PET Positron emission tomography, WB1SUVmax Whole-body 1 standardized uptake value, WB2SUVmax Whole-body 2 standardized uptake value, PCI Peritoneal cancer index, ECOG PS Eastern cooperative oncology group performance status, NA Not available, AUC Area under the curve, OR Odds ratio, 95% CI 95% confidence interval