Fig. 1

Weight gain and Lee Index are decreased by subchronic HESc treatment. Wistar lean (CTRL) and obese (MSG) rats received daily (v) isotonic saline administration, whereas some obese were treated with 500 mg/kg HESc (MSG-Syz), for 30 days. a: Weight gain curve of all groups measured weekly from weaning. b: Percentual delta change of body weight during treatment. c: Lee Index before and after treatment. In A and C values are expressed as mean ± SEM. In B data expressed as median, quartiles and range. n = 7–9 (p < 0.05). a: vs CTRL; b: vs MSG; c: vs MSG-Syz