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Table 1 Clinical, anthropometric and laboratory characteristics of studied groups

From: Association of miRNA − 320 expression level and its target gene endothelin-1 with the susceptibility and clinical features of polycystic ovary syndrome

  Control group (mean ± SD)
(n = 40)
PCO patients (mean ± SD)
(n = 60)
P
Systolic blood pressure (mm Hg) 125.4 ± 7.16 130.6 ± 7.3 <0.001*
Diastolic blood pressure (mm Hg) 85.6 ± 3.96 87.5 ± 4.9 <0.001*
Hirsutism score 5.38 ± 0.594 7.41 ± 3.02 <0.001*
Body mass index (kg/m2) 24.9 ± 2.48 33.2 ± 5.731 <0.001*
Waist/hip ratio 0.98 ± 0.191 1.26 ± 0.28 <0.001*
Ovarian volume 3.58 ± 0.612 7.35 ± 2.744 <0.001*
AFC 2.58 ± 0.612 7.35 ± 2.744 <0.001*
Total cholesterol (mg/dL) 167.5 ± 19.26 185.0 ± 124.7 <0.001*
Triglycerides (mg/dL) 144.55 ± 20.4 192.2 ± 42.05 <0.001*
LDL cholesterol (mg/dL) 106.24 ± 4.24 125.8 ± 18.11 <0.001*
HDL cholesterol (mg/dL) 57.5 ± 7.33 40.3 ± 9.42 <0.001*
Fasting plasma glucose (mg/dL) 83.9 ± 8.40 95.3 ± 15.61 <0.001*
HbA1c (%) 5.5 ± 0.596 6.03 ± 0.42 <0.001*
Fasting serum insulin (lU/mL) 6.8 ± 1.44 17.5 ± 10.41 <0.001*
HOMA-IR 1.42 ± 0.322 3.7 ± 2.32 <0.001*
HOMA-β 166.9 ± 76.9 127.7 ± 81.84 0.016
FSH (mIU/mL) 4.8 ± 0.972 5.5 ± 1.538 <0.001*
LH (mIU/mL) 5.52 ± 1.21 6.97 ± 1.53 <0.001*
LH/FSH 1.2 ± 0.43 13 ± 0.39 0.145
DHEA-S (mg/mL) 0.99 ± 0.31 1.3 ± 0.77 <0.001*
Androstenedione (ng/mL) 1.17 ± 0.34 1.7 ± 0.5 0.015
Total testosterone (ng/mL) 0.50 ± 0.145 0.7 ± 0.32 <0.001*
  1. FSI fasting serum insulin, FPG fasting plasma glucose, AFC antral follicle cells, HOMA-IR homeostasis model assessments of insulin resistance, DHEA dehydroepiandrosterone, *P < 0.05 when compared with control group