Skip to main content

Table 2 Clinical, anthropometric and laboratory characteristics of studied groups

From: Association of miRNA − 320 expression level and its target gene endothelin-1 with the susceptibility and clinical features of polycystic ovary syndrome

 

Control group(mean ± SD) (n = 40)

Non-IR group (mean ± SD) (n = 25)

IR group (mean ± SD) (n = 35)

P 1

P2

P3

SBP (mm Hg)

125.4 ± 7.16

126.96 ± 8.33

133.2 ± 5.19

0.37

<0.001*

<0.001*

DBP (mm Hg)

85.6 ± 3.96

86.28 ± 4.39

88.37 ± 5.1

0.555

0.009

0.104

Hirsutism score

5.38 ± 0.594

7.34 ± 4.49

7.45 ± 1.2

<0.001*

<0.001*

0.893

Body mass index (kg/m2)

24.9 ± 2.48

29.1 ± 5.96

36.18 ± 3.2

<0.001*

<0.001*

<0.001*

Waist/hip ratio

0.98 ± 0.191

1.11 ± 0.28

1.36 ± 0.2

<0.05*

<0.001*

<0.001*

Ovarian volume

3.58 ± 0.612

7.2 ± 4.56

7.85 ± 1.437

<0.001*

<0.001*

0.467

AFC

2.58 ± 0.612

7.3 ± 4.02

7.37 ± 1.285

<0.001*

<0.001*

0.952

Total cholesterol (mg/dL)

167.5 ± 19.26

167.1 ± 25.15

197.8 ± 14.4

0.916

<0.001*

<0.001*

Triglycerides (mg/dL)

144.55 ± 20.4

193.2 ± 58.2

191.6 ± 25.9

<0.001*

<0.001*

0.883

LDL cholesterol (mg/dL)

106.24 ± 4.24

114.3 ± 17.4

134.06 ± 13.6

0.01

<0.001*

<0.001*

HDL cholesterol (mg/dL)

57.5 ± 7.33

45.8 ± 9.27

36.4 ± 7.48

<0.001*

<0.001*

<0.001*

Fasting plasma glucose (mg/dL)

83.9 ± 8.40

93.7 ± 16.19

96.4 ± 15.3

<0.001*

<0.001*

0.516

HbA1c (%)

5.5 ± 0.596

5.8 ± 0.171

6.18 ± 0.49

0.01

<0.001*

<0.001*

Fasting serum insulin (lU/mL)

6.8 ± 1.44

7.2 ± 1.29

24.97 ± 7.17

0.755

<0.001*

<0.001*

HOMA-IR

1.42 ± 0.322

1.65 ± 0.3

5.25 ± 1.92

0.448

<0.001*

<0.001*

HOMA-β

166.9 ± 76.9

149.3 ± 18.3

86.2 ± 22.5

0.384

<0.001*

<0.001*

FSH (mIU/mL)

4.8 ± 0.972

5.14 ± 1.27

5.85 ± 1.65

0.313

<0.001*

0.078

LH (mIU/mL)

5.52 ± 1.21

6.1 ± 1.2

7.59 ± 1.4

0.081

<0.001*

<0.001*

LH/FSH

1.2 ± 0.43

7.59 ± 1.4

1.3 ± 0.4

0.778

<0.001*

0.121

DHEA-S (mg/mL)

0.99 ± 0.31

0.99 ± 0.34

1.5 ± 0.91

0.967

<0.001*

<0.001*

Androstenedione (ng/mL)

1.17 ± 0.34

1.35 ± 0.48

2.07 ± 0.46

0.103

<0.001*

<0.001*

Total testosterone (ng/mL)

0.50 ± 0.145

0.62 ± 0.28

0.9 ± 0.3

0.062

<0.001*

<0.001*

  1. IR; FSI fasting serum insulin, FPG fasting plasma glucose, AFC antral follicle cells, HOMA-IR homeostasis model assessments of insulin resistance, DHEA dehydroepiandrosterone
  2. 1Significant P values (P < 0.05) when compared non-IR group with control group
  3. 2Significant P values (P < 0.05) when compared IR group with control group 3Significant P values (P < 0.05) when compared non-IR group with IR group