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Table 2 Clinical, anthropometric and laboratory characteristics of studied groups

From: Association of miRNA − 320 expression level and its target gene endothelin-1 with the susceptibility and clinical features of polycystic ovary syndrome

  Control group(mean ± SD) (n = 40) Non-IR group (mean ± SD) (n = 25) IR group (mean ± SD) (n = 35) P 1 P2 P3
SBP (mm Hg) 125.4 ± 7.16 126.96 ± 8.33 133.2 ± 5.19 0.37 <0.001* <0.001*
DBP (mm Hg) 85.6 ± 3.96 86.28 ± 4.39 88.37 ± 5.1 0.555 0.009 0.104
Hirsutism score 5.38 ± 0.594 7.34 ± 4.49 7.45 ± 1.2 <0.001* <0.001* 0.893
Body mass index (kg/m2) 24.9 ± 2.48 29.1 ± 5.96 36.18 ± 3.2 <0.001* <0.001* <0.001*
Waist/hip ratio 0.98 ± 0.191 1.11 ± 0.28 1.36 ± 0.2 <0.05* <0.001* <0.001*
Ovarian volume 3.58 ± 0.612 7.2 ± 4.56 7.85 ± 1.437 <0.001* <0.001* 0.467
AFC 2.58 ± 0.612 7.3 ± 4.02 7.37 ± 1.285 <0.001* <0.001* 0.952
Total cholesterol (mg/dL) 167.5 ± 19.26 167.1 ± 25.15 197.8 ± 14.4 0.916 <0.001* <0.001*
Triglycerides (mg/dL) 144.55 ± 20.4 193.2 ± 58.2 191.6 ± 25.9 <0.001* <0.001* 0.883
LDL cholesterol (mg/dL) 106.24 ± 4.24 114.3 ± 17.4 134.06 ± 13.6 0.01 <0.001* <0.001*
HDL cholesterol (mg/dL) 57.5 ± 7.33 45.8 ± 9.27 36.4 ± 7.48 <0.001* <0.001* <0.001*
Fasting plasma glucose (mg/dL) 83.9 ± 8.40 93.7 ± 16.19 96.4 ± 15.3 <0.001* <0.001* 0.516
HbA1c (%) 5.5 ± 0.596 5.8 ± 0.171 6.18 ± 0.49 0.01 <0.001* <0.001*
Fasting serum insulin (lU/mL) 6.8 ± 1.44 7.2 ± 1.29 24.97 ± 7.17 0.755 <0.001* <0.001*
HOMA-IR 1.42 ± 0.322 1.65 ± 0.3 5.25 ± 1.92 0.448 <0.001* <0.001*
HOMA-β 166.9 ± 76.9 149.3 ± 18.3 86.2 ± 22.5 0.384 <0.001* <0.001*
FSH (mIU/mL) 4.8 ± 0.972 5.14 ± 1.27 5.85 ± 1.65 0.313 <0.001* 0.078
LH (mIU/mL) 5.52 ± 1.21 6.1 ± 1.2 7.59 ± 1.4 0.081 <0.001* <0.001*
LH/FSH 1.2 ± 0.43 7.59 ± 1.4 1.3 ± 0.4 0.778 <0.001* 0.121
DHEA-S (mg/mL) 0.99 ± 0.31 0.99 ± 0.34 1.5 ± 0.91 0.967 <0.001* <0.001*
Androstenedione (ng/mL) 1.17 ± 0.34 1.35 ± 0.48 2.07 ± 0.46 0.103 <0.001* <0.001*
Total testosterone (ng/mL) 0.50 ± 0.145 0.62 ± 0.28 0.9 ± 0.3 0.062 <0.001* <0.001*
  1. IR; FSI fasting serum insulin, FPG fasting plasma glucose, AFC antral follicle cells, HOMA-IR homeostasis model assessments of insulin resistance, DHEA dehydroepiandrosterone
  2. 1Significant P values (P < 0.05) when compared non-IR group with control group
  3. 2Significant P values (P < 0.05) when compared IR group with control group 3Significant P values (P < 0.05) when compared non-IR group with IR group