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Fig. 6 | Journal of Ovarian Research

Fig. 6

From: Mitochondrially targeted p53 or DBD subdomain is superior to wild type p53 in ovarian cancer cells even with strong dominant negative mutant p53

Fig. 6

TMRE assay was performed in (a) ID8 and (b) Kuramochi cell lines (24 h post transfection). TMRE detects mitochondrial outer membrane permeabilization, which occurs as a result of Bak and Bax pore formation, a hallmark of intrinsic apoptosis. Error bars represent standard deviations from triplicates (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001

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