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Fig. 6 | Journal of Ovarian Research

Fig. 6

From: Melatonin attenuates palmitic acid-induced mouse granulosa cells apoptosis via endoplasmic reticulum stress

Fig. 6

Effects of melatonin on PA-induced mouse granulosa cell apoptosis and apoptosis-related gene expression. a Effects of different concentrations of melatonin (0.1-100 μM) on PA-induced mouse granulosa cell apoptosis after 24 h. b Caspase 3 activity in mouse granulosa cells after treatment with different concentrations of melatonin (0.1-100 μM) and 400 μM PA for 24 h. c Relative BAX expression in mouse granulosa cells after treatment with different concentrations of melatonin (0.1-100 μM) and 400 μM PA for 24 h. BAX expression was normalized to the level of β-actin expression. The statistical analysis results are shown in the bar graphs. Data are presented as the mean ± SEM of three independent experiments. Bars with different letters are significantly different (p < 0.05)

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