0.05); TFSR was 100% in OBC, NS and TS. No significant differences in TRR (p > 0.05); AF were found only in OBC; TFSR was 100% after transplantation; significantly higher FGR in the 2.5 months compared to the 1.5 months-group (p  < 0.05). AMH- and E2-level in group 1 and 3 were significantly higher than in group 2 (p < 0.05); in contrast, FSH was significantly lower. Conclusions After transplantation in the mice, the thawed ovarian tissue survived and follicles developed. The ovarian fossa site was the best site for transplantation. Our animal experiments can verify that our human ovarian tissue cryopreservation technique can preserve the quality of ovarian tissue. This is the essential precondition for successful re-transplantation into the patients after performing chemo/radiotherapy to protect ovarian function and fertility."/>
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Table 1 TFSR and FGR of frozen thawed human ovarian tissue after transplantation into nude mice

From: Randomized study to prove the quality of human ovarian tissue cryopreservation by xenotransplantation into mice

Groups Primordial follicles Primary follicles Secondary follicles Antral follicles Albicans TFSR(%) FGR(%)
subcutaneous neck 62 3 0 0 5 100 4.62
ovarian bursa cavity 89 5 0 5 7 100 10.1
subutaneous thigh 56 0 0 0 3 100 0
χ 2 1.62
p -value 0.20*
  1. Note: *Considering the FGR of subutaneous thigh is 0, χ2 test for FGR between subcutaneous neck group and ovarian bursa cavity group was only conducted, which showed there was no statistical difference between those two groups (p > 0.05);TFSR (total follicle surviving rate),FGR (follicle growth rate)