Fig. 3

Targeted regulation of ATM by miR-203a-3p. Note: a-b, The binding sites of miR-203a-3p in ATM as predicted by the public databases miRDB (a) and microRNA.org (b); c-d, miR-203a-3p regulates ATM expression, as confirmed by dual-luciferase reporter gene assays in A2780 cells (c) and SKOV3cells (d). The same letters indicate nonsignificant differences, P > 0.05, and the different letters indicate statistically significant differences, P < 0.05