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Table 4 Proteins with more hub and bottlenecks

From: Proteome profiling of low grade serous ovarian cancer

Num Hub and bottleneck Protein Name Degree Betweeness
1 ACTB actin beta(ACTB) 913 0.873
2 APOA1 apolipoprotein A1(APOA1) 261 0.222
3 PRDX2 peroxiredoxin 2(PRDX2) 148 0.202
4 TAGLN transgelin(TAGLN) 70 0.114
5 HP haptoglobin(HP) 58 0.048
6 KRT1 keratin 1(KRT1) 31 0.036
7 CFL1 cofilin 1(CFL1) 13 0.008
8 APP amyloid beta precursor protein(APP) 11 0.026
9 ESR1 estrogen receptor 1(ESR1) 11 0.026
10 APOE apolipoprotein E(APOE) 11 0.009
11 NCF1 neutrophil cytosolic factor 1(NCF1) 10 0.008
12 VCAM1 vascular cell adhesion molecule 1(VCAM1) 10 0.005
13 SMAD3 SMAD family member 3(SMAD3) 9 0.004
14 TINF2 TERF1 interacting nuclear factor 2(TINF2) 8 0.008
15 FN1 fibronectin 1(FN1) 7 0.026
16 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta(YWHAZ) 7 0.005
17 TTR transthyretin(TTR) 6 0.016
18 JUN Jun proto-oncogene, AP-1 transcription factor subunit(JUN) 6 0.007
19 PPARG peroxisome proliferator activated receptor gamma(PPARG) 5 0.005
20 FBLN1 fibulin 1(FBLN1) 4 0.017
21 KRT9 keratin 9(KRT9) 4 0.016
22 ACD adrenocortical dysplasia homolog(ACD) 4 0.008
23 POT1 protection of telomeres 1(POT1) 4 0.008
24 RAD52 RAD52 homolog, DNA repair protein(RAD52) 4 0.005
25 CDC37 cell division cycle 37(CDC37) 4 0.005
26 NFKB1 nuclear factor kappa B subunit 1(NFKB1) 4 0.005
27 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1(OTUB1) 4 0.005
28 UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked(UTY) 4 0.005
29 GRB2 growth factor receptor bound protein 2(GRB2) 4 0.004