Table 4 Proteins with more hub and bottlenecks
Num | Hub and bottleneck | Protein Name | Degree | Betweeness |
|---|---|---|---|---|
1 | ACTB | actin beta(ACTB) | 913 | 0.873 |
2 | APOA1 | apolipoprotein A1(APOA1) | 261 | 0.222 |
3 | PRDX2 | peroxiredoxin 2(PRDX2) | 148 | 0.202 |
4 | TAGLN | transgelin(TAGLN) | 70 | 0.114 |
5 | HP | haptoglobin(HP) | 58 | 0.048 |
6 | KRT1 | keratin 1(KRT1) | 31 | 0.036 |
7 | CFL1 | cofilin 1(CFL1) | 13 | 0.008 |
8 | APP | amyloid beta precursor protein(APP) | 11 | 0.026 |
9 | ESR1 | estrogen receptor 1(ESR1) | 11 | 0.026 |
10 | APOE | apolipoprotein E(APOE) | 11 | 0.009 |
11 | NCF1 | neutrophil cytosolic factor 1(NCF1) | 10 | 0.008 |
12 | VCAM1 | vascular cell adhesion molecule 1(VCAM1) | 10 | 0.005 |
13 | SMAD3 | SMAD family member 3(SMAD3) | 9 | 0.004 |
14 | TINF2 | TERF1 interacting nuclear factor 2(TINF2) | 8 | 0.008 |
15 | FN1 | fibronectin 1(FN1) | 7 | 0.026 |
16 | YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta(YWHAZ) | 7 | 0.005 |
17 | TTR | transthyretin(TTR) | 6 | 0.016 |
18 | JUN | Jun proto-oncogene, AP-1 transcription factor subunit(JUN) | 6 | 0.007 |
19 | PPARG | peroxisome proliferator activated receptor gamma(PPARG) | 5 | 0.005 |
20 | FBLN1 | fibulin 1(FBLN1) | 4 | 0.017 |
21 | KRT9 | keratin 9(KRT9) | 4 | 0.016 |
22 | ACD | adrenocortical dysplasia homolog(ACD) | 4 | 0.008 |
23 | POT1 | protection of telomeres 1(POT1) | 4 | 0.008 |
24 | RAD52 | RAD52 homolog, DNA repair protein(RAD52) | 4 | 0.005 |
25 | CDC37 | cell division cycle 37(CDC37) | 4 | 0.005 |
26 | NFKB1 | nuclear factor kappa B subunit 1(NFKB1) | 4 | 0.005 |
27 | OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1(OTUB1) | 4 | 0.005 |
28 | UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked(UTY) | 4 | 0.005 |
29 | GRB2 | growth factor receptor bound protein 2(GRB2) | 4 | 0.004 |