Table 1 Correlation between level of TERT promoter methylation and response to ATRA at the end of treatment (day 7)
Cell line | TERT methylation | ATRA treatment | ||
|---|---|---|---|---|
Cellular growth | Cell viability | TERT expression | ||
OVCAR3 | Low | ↘ | ↘ | ↘ |
PAI1 | Intermediate | ↘ | ↘ | ↘ |
SKOV3 | Intermediate | ↘ | ↘ | ↘ |
A2780 | High | → | → | ↗ |
CAOV3 | High | → | → | ↗ |
OVMZ6 | High | → | → | ↗ |
OVMZ36 | High | → | → | ↗ |
OVMZ37 | High | → | → | ↗ |