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Table 2 Neonatal outcomes of singleton live births in fresh ET and FET cycles

From: Neonatal outcomes of singleton live births with vanishing twin syndrome following double embryos transfer in assisted reproductive technology: a retrospective cohort study

Fresh cycles

Frozen cycles

 

Study group

N = 1196

Control group

N = 1576

P value

OR, 95% CI

Adjusted

P value

Adjusted

OR, 95% CI

Study group

N = 1275

Control group

N = 2173

P value

OR, 95% CI

Adjusted

P value

Adjusted

OR, 95% CI

Gestational age

262.8 ± 8.4

268.9 ± 13.9

0.000

/

/

/

263.0 ± 15.7

273.0 ± 10.5

0.000

/

/

/

PTB

258 (21.6)

159 (10.1)

0.000

2.45(1.98–3.03)

0.000*

2.41(1.93–2.99)

230 (18.0)

160 (7.4)

0.000

2.77 (2.23,3.43)

0.000*

2.68 (2.15,3.33)

birthweight

2962.4 ± 563.1

3104.9 ± 498.5

0.000

/

/

/

3099 ± 662.1

3352 ± 671.5

0.000

/

/

/

LBW

201(16.8)

138 (8.8)

0.000

2.11 (1.67–2.65)

0.000*

2.21 (1.74–2.80)

204 (16.0)

145 (6.6)

0.000

2.67 (2.13–3.34)

0.000*

2.07 (2.12,3.35)

SGA

90 (7.5)

111 (7.1)

0.561

1.09 (0.82–1.45)

0.960

1.01 (0.75,1.35)

60 (4.7)

104 (4.8)

0.915

0.98 (0.71–1.36)

0.730

0.94 (0.68,1.31)

Congenital malformation

20 (1.7)

28 (1.8)

0.835

0.94 (0.53–1.68)

0.640

0.87 (0.48–1.57)

25 (2.0)

43 (19.8)

0.971

0.99 (0.60,1.63)

0.940

0.98 (0.59,1.62)

Pediatrics admission

280 (23.4)

169 (10.7)

0.000

2.55 (2.07–3.13)

0.000*

2.62 (2.12–3.24)

256 (20.1)

190 (8.7)

0.000

2.62 (2.14–3.21)

0.000*

2.60 (2.12,3.19)

NICU admission

60 (5.0)

26 (1.6)

0.001

1.98 (1.32,2.96)

0.001*

2.04 (1.36,3.08)

46 (3.6)

36 (1.7)

0.000

2.22 (1.43,3.46)

0.001*

2.21 (1.41,3.44)

  1. *p < 0.05 was statistically significant. Adjusted for confounders, including age of women, BMI, value of AMH, infertile years, current cycle, AFC, cause of infertility, number of oocytes retrieved, endometrial thickness at the day of transplantation, number of high-quality embryos, embryo stage