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Table 2 Neonatal outcomes of singleton live births in fresh ET and FET cycles

From: Neonatal outcomes of singleton live births with vanishing twin syndrome following double embryos transfer in assisted reproductive technology: a retrospective cohort study

Fresh cycles Frozen cycles
  Study group
N = 1196
Control group
N = 1576
P value OR, 95% CI Adjusted
P value
Adjusted
OR, 95% CI
Study group
N = 1275
Control group
N = 2173
P value OR, 95% CI Adjusted
P value
Adjusted
OR, 95% CI
Gestational age 262.8 ± 8.4 268.9 ± 13.9 0.000 / / / 263.0 ± 15.7 273.0 ± 10.5 0.000 / / /
PTB 258 (21.6) 159 (10.1) 0.000 2.45(1.98–3.03) 0.000* 2.41(1.93–2.99) 230 (18.0) 160 (7.4) 0.000 2.77 (2.23,3.43) 0.000* 2.68 (2.15,3.33)
birthweight 2962.4 ± 563.1 3104.9 ± 498.5 0.000 / / / 3099 ± 662.1 3352 ± 671.5 0.000 / / /
LBW 201(16.8) 138 (8.8) 0.000 2.11 (1.67–2.65) 0.000* 2.21 (1.74–2.80) 204 (16.0) 145 (6.6) 0.000 2.67 (2.13–3.34) 0.000* 2.07 (2.12,3.35)
SGA 90 (7.5) 111 (7.1) 0.561 1.09 (0.82–1.45) 0.960 1.01 (0.75,1.35) 60 (4.7) 104 (4.8) 0.915 0.98 (0.71–1.36) 0.730 0.94 (0.68,1.31)
Congenital malformation 20 (1.7) 28 (1.8) 0.835 0.94 (0.53–1.68) 0.640 0.87 (0.48–1.57) 25 (2.0) 43 (19.8) 0.971 0.99 (0.60,1.63) 0.940 0.98 (0.59,1.62)
Pediatrics admission 280 (23.4) 169 (10.7) 0.000 2.55 (2.07–3.13) 0.000* 2.62 (2.12–3.24) 256 (20.1) 190 (8.7) 0.000 2.62 (2.14–3.21) 0.000* 2.60 (2.12,3.19)
NICU admission 60 (5.0) 26 (1.6) 0.001 1.98 (1.32,2.96) 0.001* 2.04 (1.36,3.08) 46 (3.6) 36 (1.7) 0.000 2.22 (1.43,3.46) 0.001* 2.21 (1.41,3.44)
  1. *p < 0.05 was statistically significant. Adjusted for confounders, including age of women, BMI, value of AMH, infertile years, current cycle, AFC, cause of infertility, number of oocytes retrieved, endometrial thickness at the day of transplantation, number of high-quality embryos, embryo stage