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Table 1 Clinical data of enrolled patients according to the embryo selection method

From: Impact of the addition of Early Embryo Viability Assessment to morphological evaluation on the accuracy of embryo selection on day 3 or day 5: a retrospective analysis

 

All

DET-3 M

DET-3 ME

SET-5 M

SET-5 ME

p

(n = 328)

(n = 106)

(n = 48)

(n = 126)

(n = 48)

Age (years)

34.6 ± 3.0

34.7 ± 3.4

34.8 ± 3.0

34.2 ± 2.9

34.9 ± 1.9

ns

BMI (kg/m2)

23.6 ± 3.9

23.1 ± 3.6

23.2 ± 4.2

24.1 ± 4.2

24.6 ± 3.5

ns

Day 3 FSH (IU/I)

6.9 ± 1.5

7.1 ± 1.7

6.7 ± 1.3

6.7 ± 1.3

6.9 ± 1.8

ns

AMH (ng/ml)

3.7 ± 2.5

3.3 ± 1.9

3.0 ± 1.8

4.6 ± 3.2

3.6 ± 2.0

ns

AFC

15.4 ± 7.3

14.3 ± 6.0

15.4 ± 9.4

16.9 ± 8.2

15.2 ± 5.5

ns

Total exogenous FSH (IU)

2083.7 ± 823.7

2245.2 ± 940.7

2112.0 ± 841.0

1902.2 ± 671.2

2026.2 ± 736.7

ns

Peak E2 (pg/ml)

2437.2 ± 1097.9

1933.9 ± 867

1672.9 ± 1178.3

2211.3 ± 1171.1

2436.3 ± 1317.3

ns

OSI

6.6 ± 3.8

5.3 ± 3.0

5.5 ± 3.6

7.9 ± 3.6

8.3 ± 5.2

< 0.05*

Endometrial thickness (mm)

10.4 ± 2.0

10.2 ± 1.8

10.0 ± 2.2

10.7 ± 2.2

10.6 ± 1.7

ns

Retrieved oocytes

11.6 ± 4.0

10.2 ± 3.0

9.5 ± 2.6

13.4 ± 4.2

13.8 ± 4.9

< 0.05*

Mature (MII) oocytes (%)

83.5 ± 15.2

85.6 ± 12.6

78.1 ± 19.5

81.8 ± 15.6

89.1 ± 12.6

ns

Insemination technique (%)

ns

IVF

24 (40/164)

26 (14/53)

25 (6/24)

25 (16/63)

17 (4/24)

 

ICSI

76 (124/164)

74 (39/53)

75 (18/24)

75 (47/63)

83 (20/24)

 

Fertilized (2PN) oocytes (%)

74.4 ± 17.6

69.8 ± 18.6

72.8 ± 18.3

79.7 ± 15.2

76.7 ± 16.6

ns

Cleaved embryos (%)

97.3 ± 7.9

96.8 ± 7.7

96.3 ± 11.6

98.0 ± 6.3

98.2 ± 7.1

ns

  1. DET-3 M = patients receiving two day 3 embryos selected by IMCS; DET-3 ME = patients receiving two day 3 embryos selected by standard morphology plus Eeva™ score; SET-5 M = patients receiving one day 5 blastocyst selected by IMCS plus blastocyst morphological score; SET-5 ME = patients receiving one day 5 blastocyst selected by blastocyst morphological score plus Eeva™. AFC = antral follicle count. OSI = ovarian sensitivity index (retrieved oocytes × 1000 / total FSH dose). Data are expressed as mean ± SD or as absolute value and percentage. * Significance is referred to the comparison of both SET subgroups (SET-5 M and SET-5 ME) vs. both DET subgroups (DET-3 M and DET-3 ME)