TY - JOUR AU - Hengartner, M. O. PY - 2000 DA - 2000// TI - The biochemistry of apoptosis JO - Nature. VL - 407 UR - https://doi.org/10.1038/35037710 DO - 10.1038/35037710 ID - Hengartner2000 ER - TY - JOUR AU - Fulda, S. AU - Debatin, K. M. PY - 2006 DA - 2006// TI - Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy JO - Oncogene. VL - 25 UR - https://doi.org/10.1038/sj.onc.1209608 DO - 10.1038/sj.onc.1209608 ID - Fulda2006 ER - TY - JOUR AU - Degterev, A. AU - Boyce, M. AU - Yuan, J. PY - 2003 DA - 2003// TI - A decade of caspases JO - Oncogene. VL - 22 UR - https://doi.org/10.1038/sj.onc.1207107 DO - 10.1038/sj.onc.1207107 ID - Degterev2003 ER - TY - JOUR AU - Saelens, X. AU - Festjens, N. AU - Vande Walle, L. AU - Gurp, M. AU - Loo, G. AU - Vandenabeele, P. PY - 2004 DA - 2004// TI - Toxic proteins released from mitochondria in cell death JO - Oncogene. VL - 23 UR - https://doi.org/10.1038/sj.onc.1207523 DO - 10.1038/sj.onc.1207523 ID - Saelens2004 ER - TY - JOUR AU - Fulda, S. PY - 2015 DA - 2015// TI - Promises and challenges of Smac mimetics as Cancer therapeutics JO - Clin Cancer Res VL - 21 UR - https://doi.org/10.1158/1078-0432.CCR-15-0365 DO - 10.1158/1078-0432.CCR-15-0365 ID - Fulda2015 ER - TY - JOUR AU - Varfolomeev, E. AU - Blankenship, J. W. AU - Wayson, S. M. AU - Fedorova, A. V. AU - Kayagaki, N. AU - Garg, P. PY - 2007 DA - 2007// TI - IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis JO - Cell. VL - 131 UR - https://doi.org/10.1016/j.cell.2007.10.030 DO - 10.1016/j.cell.2007.10.030 ID - Varfolomeev2007 ER - TY - JOUR AU - Vince, J. E. AU - Wong, W. W. -. L. AU - Khan, N. AU - Feltham, R. AU - Chau, D. AU - Ahmed, A. U. PY - 2007 DA - 2007// TI - IAP antagonists target cIAP1 to induce TNFα-dependent apoptosis JO - Cell. VL - 131 UR - https://doi.org/10.1016/j.cell.2007.10.037 DO - 10.1016/j.cell.2007.10.037 ID - Vince2007 ER - TY - JOUR AU - Petersen, S. L. AU - Wang, L. AU - Yalcin-Chin, A. AU - Li, L. AU - Peyton, M. AU - Minna, J. PY - 2007 DA - 2007// TI - Autocrine TNFα signaling renders human Cancer cells susceptible to Smac-mimetic-induced apoptosis JO - Cancer Cell VL - 12 UR - https://doi.org/10.1016/j.ccr.2007.08.029 DO - 10.1016/j.ccr.2007.08.029 ID - Petersen2007 ER - TY - JOUR AU - Lu, J. AU - Bai, L. AU - Sun, H. AU - Nikolovska-Coleska, Z. AU - McEachern, D. AU - Qiu, S. PY - 2008 DA - 2008// TI - SM-164: a novel, bivalent Smac mimetic that induces apoptosis and tumor regression by concurrent removal of the blockade of cIAP-1/2 and XIAP JO - Cancer Res VL - 68 UR - https://doi.org/10.1158/0008-5472.CAN-08-2655 DO - 10.1158/0008-5472.CAN-08-2655 ID - Lu2008 ER - TY - JOUR AU - Vischioni, B. AU - Valk, P. AU - Span, S. W. AU - Kruyt, F. A. E. AU - Rodriguez, J. A. AU - Giaccone, G. PY - 2006 DA - 2006// TI - Expression and localization of inhibitor of apoptosis proteins in normal human tissues JO - Hum Pathol VL - 37 UR - https://doi.org/10.1016/j.humpath.2005.09.022 DO - 10.1016/j.humpath.2005.09.022 ID - Vischioni2006 ER - TY - JOUR AU - Jamieson, S. AU - Fuller, P. J. PY - 2012 DA - 2012// TI - Molecular pathogenesis of granulosa cell tumors of the ovary JO - Endocr Rev VL - 33 UR - https://doi.org/10.1210/er.2011-0014 DO - 10.1210/er.2011-0014 ID - Jamieson2012 ER - TY - JOUR AU - Zhou, J. AU - Chen, Y. AU - Huang, Y. AU - Long, J. AU - Wan, F. AU - Zhang, S. PY - 2013 DA - 2013// TI - Serum follicle-stimulating hormone level is associated with human epidermal growth factor receptor type 2 and Ki67 expression in post-menopausal females with breast cancer JO - Oncol Lett VL - 6 UR - https://doi.org/10.3892/ol.2013.1516 DO - 10.3892/ol.2013.1516 ID - Zhou2013 ER - TY - STD TI - Gründker C, Emons G. The Role of Gonadotropin-Releasing Hormone in Cancer Cell Proliferation and Metastasis. Frontiers in Endocrinology. 2017;8(187). ID - ref13 ER - TY - JOUR AU - Lagana, A. S. AU - Colonese, F. AU - Colonese, E. AU - Sofo, V. AU - Salmeri, F. M. AU - Granese, R. PY - 2015 DA - 2015// TI - Cytogenetic analysis of epithelial ovarian cancer's stem cells: an overview on new diagnostic and therapeutic perspectives JO - Eur J Gynaecol Oncol VL - 36 ID - Lagana2015 ER - TY - JOUR AU - Lagana, A. S. AU - Sofo, V. AU - Vitale, S. G. AU - Triolo, O. PY - 2016 DA - 2016// TI - Epithelial ovarian cancer inherent resistance: may the pleiotropic interaction between reduced immunosurveillance and drug-resistant cells play a key role? JO - Gynecologic oncology reports VL - 18 UR - https://doi.org/10.1016/j.gore.2016.09.004 DO - 10.1016/j.gore.2016.09.004 ID - Lagana2016 ER - TY - JOUR AU - Nishi, Y. AU - Yanase, T. AU - Mu, Y. AU - Oba, K. AU - Ichino, I. AU - Saito, M. PY - 2001 DA - 2001// TI - Establishment and characterization of a steroidogenic human granulosa-like tumor cell line, KGN, that expresses functional follicle-stimulating hormone receptor JO - Endocrinology. VL - 142 UR - https://doi.org/10.1210/endo.142.1.7862 DO - 10.1210/endo.142.1.7862 ID - Nishi2001 ER - TY - JOUR AU - Leung, D. T. H. AU - Nguyen, T. AU - Oliver, E. M. AU - Matti, J. AU - Alexiadis, M. AU - Silke, J. PY - 2019 DA - 2019// TI - Combined PPARγ activation and XIAP inhibition as a potential therapeutic strategy for ovarian granulosa cell tumors JO - Mol Cancer Ther VL - 18 UR - https://doi.org/10.1158/1535-7163.MCT-18-0078 DO - 10.1158/1535-7163.MCT-18-0078 ID - Leung2019 ER - TY - JOUR AU - Zhang, Y. AU - Yan, Z. AU - Qin, Q. AU - Nisenblat, V. AU - Chang, H. M. AU - Yu, Y. PY - 2018 DA - 2018// TI - Transcriptome Landscape of Human Folliculogenesis Reveals Oocyte and Granulosa Cell Interactions JO - Molecular cell VL - 72 UR - https://doi.org/10.1016/j.molcel.2018.10.029 DO - 10.1016/j.molcel.2018.10.029 ID - Zhang2018 ER - TY - JOUR AU - Imai, M. AU - Muraki, M. AU - Takamatsu, K. AU - Saito, H. AU - Seiki, M. AU - Takahashi, Y. PY - 2008 DA - 2008// TI - Spontaneous transformation of human granulosa cell tumours into an aggressive phenotype: a metastasis model cell line JO - BMC Cancer VL - 8 UR - https://doi.org/10.1186/1471-2407-8-319 DO - 10.1186/1471-2407-8-319 ID - Imai2008 ER - TY - JOUR AU - Stehlik, C. AU - Martin, R. AU - Kumabashiri, I. AU - Schmid, J. A. AU - Binder, B. R. AU - Lipp, J. PY - 1998 DA - 1998// TI - Nuclear factor (NF)-κB–regulated X-chromosome–linked iap gene expression protects endothelial cells from tumor necrosis factor α–induced apoptosis JO - J Exp Med VL - 188 UR - https://doi.org/10.1084/jem.188.1.211 DO - 10.1084/jem.188.1.211 ID - Stehlik1998 ER - TY - JOUR AU - Wang, C. -. Y. AU - Mayo, M. W. AU - Korneluk, R. G. AU - Goeddel, D. V. AU - Baldwin, A. S. PY - 1998 DA - 1998// TI - NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation JO - Science. VL - 281 UR - https://doi.org/10.1126/science.281.5383.1680 DO - 10.1126/science.281.5383.1680 ID - Wang1998 ER - TY - JOUR AU - Kang, H. B. AU - Kim, Y. E. AU - Kwon, H. J. AU - Sok, D. E. AU - Lee, Y. PY - 2007 DA - 2007// TI - Enhancement of NF-kappaB expression and activity upon differentiation of human embryonic stem cell line SNUhES3 JO - Stem Cells Dev VL - 16 UR - https://doi.org/10.1089/scd.2007.0014 DO - 10.1089/scd.2007.0014 ID - Kang2007 ER - TY - JOUR AU - Xing, L. AU - Remick, D. G. PY - 2007 DA - 2007// TI - Promoter elements responsible for antioxidant regulation of MCP-1 gene expression JO - Antioxid Redox Signal VL - 9 UR - https://doi.org/10.1089/ars.2007.1921 DO - 10.1089/ars.2007.1921 ID - Xing2007 ER - TY - JOUR AU - Noorden, C. J. F. PY - 2001 DA - 2001// TI - The history of Z-VAD-FMK, a tool for understanding the significance of caspase inhibition JO - Acta Histochem VL - 103 UR - https://doi.org/10.1078/0065-1281-00601 DO - 10.1078/0065-1281-00601 ID - Noorden2001 ER - TY - JOUR AU - Chaitanya, G. V. AU - Steven, A. J. AU - Babu, P. P. PY - 2010 DA - 2010// TI - PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration JO - Cell communication and signaling : CCS VL - 8 UR - https://doi.org/10.1186/1478-811X-8-31 DO - 10.1186/1478-811X-8-31 ID - Chaitanya2010 ER - TY - JOUR AU - Hanahan, D. AU - Weinberg, R. A. PY - 2011 DA - 2011// TI - Hallmarks of cancer: the next generation JO - Cell. VL - 144 UR - https://doi.org/10.1016/j.cell.2011.02.013 DO - 10.1016/j.cell.2011.02.013 ID - Hanahan2011 ER - TY - JOUR AU - Dubrez, L. AU - Berthelet, J. AU - Glorian, V. PY - 2013 DA - 2013// TI - IAP proteins as targets for drug development in oncology JO - OncoTargets and therapy VL - 9 UR - https://doi.org/10.2147/OTT.S33375 DO - 10.2147/OTT.S33375 ID - Dubrez2013 ER - TY - JOUR AU - Infante, J. R. AU - Dees, E. C. AU - Olszanski, A. J. AU - Dhuria, S. V. AU - Sen, S. AU - Cameron, S. PY - 2014 DA - 2014// TI - Phase I dose-escalation study of LCL161, an oral inhibitor of apoptosis proteins inhibitor, in patients with advanced solid tumors JO - Journal of clinical oncology : official journal of the American Society of Clinical Oncology VL - 32 UR - https://doi.org/10.1200/JCO.2013.52.3993 DO - 10.1200/JCO.2013.52.3993 ID - Infante2014 ER - TY - JOUR AU - Bertrand Mathieu, J. M. AU - Vandenabeele, P. PY - 2011 DA - 2011// TI - The Ripoptosome: death decision in the cytosol JO - Mol Cell VL - 43 UR - https://doi.org/10.1016/j.molcel.2011.07.007 DO - 10.1016/j.molcel.2011.07.007 ID - Bertrand Mathieu2011 ER - TY - JOUR AU - Wertz, I. E. AU - Dixit, V. M. PY - 2010 DA - 2010// TI - Signaling to NF-κB: regulation by ubiquitination JO - Cold Spring Harb Perspect Biol VL - 2 UR - https://doi.org/10.1101/cshperspect.a003350 DO - 10.1101/cshperspect.a003350 ID - Wertz2010 ER - TY - JOUR AU - Laganà, A. n. t. o. n. i. o. AU - Vitale, S. a. l. v. a. t. o. r. e. AU - Nigro, A. n. g. e. l. a. AU - Sofo, V. i. n. c. e. n. z. a. AU - Salmeri, F. r. a. n. c. e. s. c. a. AU - Rossetti, P. a. o. l. a. AU - Rapisarda, A. g. n. e. s. e. AU - La Vignera, S. a. n. d. r. o. AU - Condorelli, R. o. s. i. t. a. AU - Rizzo, G. i. a. n. l. u. c. a. AU - Buscema, M. a. s. s. i. m. o. PY - 2016 DA - 2016// TI - Pleiotropic Actions of Peroxisome Proliferator-Activated Receptors (PPARs) in Dysregulated Metabolic Homeostasis, Inflammation and Cancer: Current Evidence and Future Perspectives JO - International Journal of Molecular Sciences VL - 17 UR - https://doi.org/10.3390/ijms17070999 DO - 10.3390/ijms17070999 ID - Laganà2016 ER - TY - JOUR AU - Vitale, S. G. AU - Lagana, A. S. AU - Nigro, A. AU - Rosa, V. L. AU - Rossetti, P. AU - Rapisarda, A. M. PY - 2016 DA - 2016// TI - Peroxisome proliferator-activated receptor modulation during metabolic diseases and cancers: master and minions JO - PPAR Res VL - 2016 UR - https://doi.org/10.1155/2016/6517313 DO - 10.1155/2016/6517313 ID - Vitale2016 ER - TY - JOUR AU - Brumatti, G. AU - Ma, C. AU - Lalaoui, N. AU - Nguyen, N. Y. AU - Navarro, M. AU - Tanzer, M. C. PY - 2016 DA - 2016// TI - The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia JO - Sci Transl Med VL - 8 UR - https://doi.org/10.1126/scitranslmed.aad3099 DO - 10.1126/scitranslmed.aad3099 ID - Brumatti2016 ER - TY - JOUR AU - McComb, S. AU - Aguade-Gorgorio, J. AU - Harder, L. AU - Marovca, B. AU - Cario, G. AU - Eckert, C. PY - 2016 DA - 2016// TI - Activation of concurrent apoptosis and necroptosis by SMAC mimetics for the treatment of refractory and relapsed ALL JO - Sci Transl Med VL - 8 UR - https://doi.org/10.1126/scitranslmed.aad2986 DO - 10.1126/scitranslmed.aad2986 ID - McComb2016 ER - TY - JOUR AU - Opel, D. AU - Schnaiter, A. AU - Dodier, D. AU - Jovanovic, M. AU - Gerhardinger, A. AU - Idler, I. PY - 2015 DA - 2015// TI - Targeting inhibitor of apoptosis proteins by Smac mimetic elicits cell death in poor prognostic subgroups of chronic lymphocytic leukemia JO - Int J Cancer VL - 137 UR - https://doi.org/10.1002/ijc.29650 DO - 10.1002/ijc.29650 ID - Opel2015 ER - TY - JOUR AU - Schirmer, M. AU - Trentin, L. AU - Queudeville, M. AU - Seyfried, F. AU - Demir, S. AU - Tausch, E. PY - 2016 DA - 2016// TI - Intrinsic and chemo-sensitizing activity of SMAC-mimetics on high-risk childhood acute lymphoblastic leukemia JO - Cell Death Dis VL - 7 UR - https://doi.org/10.1038/cddis.2015.382 DO - 10.1038/cddis.2015.382 ID - Schirmer2016 ER - TY - JOUR AU - Steinhart, L. AU - Belz, K. AU - Fulda, S. PY - 2013 DA - 2013// TI - Smac mimetic and demethylating agents synergistically trigger cell death in acute myeloid leukemia cells and overcome apoptosis resistance by inducing necroptosis JO - Cell Death Dis VL - 4 UR - https://doi.org/10.1038/cddis.2013.320 DO - 10.1038/cddis.2013.320 ID - Steinhart2013 ER - TY - JOUR AU - Safferthal, C. AU - Rohde, K. AU - Fulda, S. PY - 2017 DA - 2017// TI - Therapeutic targeting of necroptosis by Smac mimetic bypasses apoptosis resistance in acute myeloid leukemia cells JO - Oncogene. VL - 36 UR - https://doi.org/10.1038/onc.2016.310 DO - 10.1038/onc.2016.310 ID - Safferthal2017 ER - TY - JOUR AU - Chen, Q. AU - Kang, J. AU - Fu, C. PY - 2018 DA - 2018// TI - The independence of and associations among apoptosis, autophagy, and necrosis JO - Signal Transduction and Targeted Therapy VL - 3 UR - https://doi.org/10.1038/s41392-018-0018-5 DO - 10.1038/s41392-018-0018-5 ID - Chen2018 ER - TY - JOUR AU - Bagnjuk, K. AU - Stöckl, J. B. AU - Fröhlich, T. AU - Arnold, G. J. AU - Behr, R. AU - Berg, U. PY - 2019 DA - 2019// TI - Necroptosis in primate luteolysis: a role for ceramide JO - Cell Death Discovery VL - 5 UR - https://doi.org/10.1038/s41420-019-0149-7 DO - 10.1038/s41420-019-0149-7 ID - Bagnjuk2019 ER - TY - JOUR AU - Beug, S. T. AU - Conrad, D. P. AU - Alain, T. AU - Korneluk, R. G. AU - Lacasse, E. C. PY - 2015 DA - 2015// TI - Combinatorial cancer immunotherapy strategies with proapoptotic small-molecule IAP antagonists JO - The International journal of developmental biology VL - 59 UR - https://doi.org/10.1387/ijdb.150084el DO - 10.1387/ijdb.150084el ID - Beug2015 ER - TY - STD TI - Beug ST, Beauregard CE, Healy C, Sanda T, St-Jean M, Chabot J, et al. Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma. Nat Commun. 2017;8. ID - ref42 ER - TY - STD TI - Fischer K, Tognarelli S, Roesler S, Boedicker C, Schubert R, Steinle A, et al. The Smac Mimetic BV6 Improves NK Cell-Mediated Killing of Rhabdomyosarcoma Cells by Simultaneously Targeting Tumor and Effector Cells. Front Immunol. 2017;8(202). ID - ref43 ER - TY - JOUR AU - Lecis, D. AU - Cesare, M. AU - Perego, P. AU - Conti, A. AU - Corna, E. AU - Drago, C. PY - 2013 DA - 2013// TI - Smac mimetics induce inflammation and necrotic tumour cell death by modulating macrophage activity JO - Cell death & disease VL - 4 UR - https://doi.org/10.1038/cddis.2013.449 DO - 10.1038/cddis.2013.449 ID - Lecis2013 ER - TY - JOUR AU - Fulda, S. PY - 2017 DA - 2017// TI - Smac mimetics to therapeutically target IAP proteins in Cancer JO - Int Rev Cell Mol Biol VL - 330 UR - https://doi.org/10.1016/bs.ircmb.2016.09.004 DO - 10.1016/bs.ircmb.2016.09.004 ID - Fulda2017 ER - TY - JOUR AU - Du, Y. AU - Bagnjuk, K. AU - Lawson, M. S. AU - Xu, J. AU - Mayerhofer, A. PY - 2018 DA - 2018// TI - Acetylcholine and necroptosis are players in follicular development in primates JO - Sci Rep VL - 8 UR - https://doi.org/10.1038/s41598-018-24661-z DO - 10.1038/s41598-018-24661-z ID - Du2018 ER - TY - JOUR AU - Blohberger, J. AU - Kunz, L. AU - Einwang, D. AU - Berg, U. AU - Berg, D. AU - Ojeda, S. R. PY - 2015 DA - 2015// TI - Readthrough acetylcholinesterase (AChE-R) and regulated necrosis: pharmacological targets for the regulation of ovarian functions? Cell death & JO - Disease. VL - 6 ID - Blohberger2015 ER - TY - JOUR AU - Koressaar, T. AU - Remm, M. PY - 2007 DA - 2007// TI - Enhancements and modifications of primer design program Primer3 JO - Bioinformatics VL - 23 UR - https://doi.org/10.1093/bioinformatics/btm091 DO - 10.1093/bioinformatics/btm091 ID - Koressaar2007 ER - TY - JOUR AU - Altschul, S. F. AU - Gish, W. AU - Miller, W. AU - Myers, E. W. AU - Lipman, D. J. PY - 1990 DA - 1990// TI - Basic local alignment search tool JO - J Mol Biol VL - 215 UR - https://doi.org/10.1016/S0022-2836(05)80360-2 DO - 10.1016/S0022-2836(05)80360-2 ID - Altschul1990 ER - TY - JOUR AU - Rueden, C. T. AU - Schindelin, J. AU - Hiner, M. C. AU - DeZonia, B. E. AU - Walter, A. E. AU - Arena, E. T. PY - 2017 DA - 2017// TI - ImageJ2: ImageJ for the next generation of scientific image data JO - BMC bioinformatics VL - 18 UR - https://doi.org/10.1186/s12859-017-1934-z DO - 10.1186/s12859-017-1934-z ID - Rueden2017 ER -