Risk factors for postoperative recurrence of ovarian endometriosis: long-term follow-up of 358 women

Table 2 Univariate and multivariate analysis of risk factors in the endometrioma and/or endometriosis-related pain recurrence and nonrecurrence groups

Factor	Univariate analysis			Multivariate analysis
Factor	Relative risk	95%CI	P value	Relative risk	95%CI	P value
Age at surgery (per 5 years)	0.764	0.615–0.949	0.015	0.738	0.520–1.048	0.090
Gravida
0	1.000
1	0.673	0.370–1.224	0.194
2 (and above)	0.757	0.557–1.029	0.075
Parity
0	1.000
1	0.478	0.261–0.876	0.017	0.002	0.000–1.222	0.974
2	0.216	0.011–4.254	0.314
BMI	0.820	0.478–1.407	0.470
Infertility	1.527	0.882–2.644	0.131
Extent of dysmenorrhea				1.711	1.175–2.493	0.005
None	1.000
Mild	4.506	1.413–14.368	0.011
Moderate	2.451	1.433–4.193	0.001
Severe	1.771	1.254–2.502	0.001
Duration of dysmenorrhea (per year)	1.120	1.054–1.190	< 0.001	1.026	0.944–1.114	0.548
Extent of dysmenorrhea	2.534	1.408–4.563	0.002
VAS (0-4)
VAS (5-10)
Dyspareunia	1.734	1.049–2.866	0.032	1.081	0.511–2.285	0.839
Chronic pelvic pain	0.959	0.503–1.828	0.898
Dyschezia	0.735	0.268–2.018	0.550
Presence of leiomyoma	1.661	0.969–2.848	0.065	1.713	0.825–3.555	0.149
Presence of adenomyosis	1.629	1.008–2.630	0.046	1.446	0.719–2.908	0.301
Presence of deep infiltrating endometriosis	1.380	0.849–2.243	0.194	1.118	0.582–2.149	0.737
CA125 level (45 U/ml)	1.856	1.072–3.214	0.021	1.020	0.965–1.078	0.491
rARSM stage	1.204	0.774–1.873	0.409
Bilateral involvement	1.046	0.650–1.684	0.853
Large dimeter (per 10 mm)	1.016	0.944–1.093	0.674
Postoperative medication
None	1.000
GnRHa	21.818	0.125–3810.382	0.242
OCP	4.057	0.019–856.392	0.610
Mirena	2.741	0.048–155.496	0.624
GnRHa+Mirena	1.991	0.375–9.730	0.436
Postoperative pregnancy	0.938	0.655–1.344	0.728	0.649	0.460–0.914	0.013

Abbreviations: BMI Body mass index, CA-125 Cancer antigen 125, GnRHa Gonadotropin-releasing hormone agonist, OCP Oral contraceptive pills, VAS Visual analogue score

ISSN: 1757-2215