Table 2 Immunohistochemical staining on the different histological components
From: Canine ovarian gonadoblastoma with dysgerminoma overgrowth: a case study and literature review
Marker | Immunohistochemical reactivity b | |||
|---|---|---|---|---|
Gonadoblastoma | Dysgerminoma | Sex cord-stromal tumour | ||
Germ cells | Sex cord-stromal cells | |||
c-KIT (CD117) | ++ | – | ++ | – |
α-inhibin | – | +++ | – | −/+++ |
Pan-cytokeratin | – | – | – | +++ |
Vimentin | + | ++ | + | ++ |
Oestrogen receptor | – | – | – | – |
EMA | – | – | – | – |
Ki-67 PI a | < 1% | – | 23% | – |