Table 3 Gonadoblastoma with normal 46, XX karyotype: data from the human literature
From: Canine ovarian gonadoblastoma with dysgerminoma overgrowth: a case study and literature review
Author (Reference) | Age (years) | Coexistence | Bilaterality | Karyotype | Clinical presentation | Treatment |
|---|---|---|---|---|---|---|
Elemenoglou et al., 1990 [32] | NA | NA | NA | 46, XX | Pregnant | NA |
Erhan et al., 1992 [33] | 26 | DYG | No | 46, XX | Pregnancy+ adnexal mass | H + BO+ CHT |
Obata et al., 1995 [34] | 10 | DYG and MGCTa (DYG+ YSC) | Yes | 46, XX | Abdominal pain | BO+ CHT |
Zhao et al., 2000 [35] | 27 | MGCT (COC+ EC+ YST+ IT) | No | 46, XX | Abdominal mass | UO+ CHT+ H+ UO+ L+ O+ HRT |
Kim et al., 2003 [19] | 33 | DYG and SCST | No | 46, XX | Abdominal mass | UO+ CHT |
Kim et al., 2003 [19] | 30 | DYG | No | 46, XX | Abdominal Pain | UO |
Erdemoglu and Ozen, 2007 [36] | 19 | EST | No | 46, XX | Abdominal mass + pain | UO |
Gorosito et al., 2010 [37] | 17 | DYG | No | 46, XX | Pregnancy+ ovarian mass | CHT+ H+ UO |
Yilmaz et al., 2010 [38] | 20 | DYG | Yes | 46, XX | Increased abdominal girth | BO+ CHT+ RT |
Koo et al., 2011 [39] | 34 | DYG | No | 46, XX | Vaginal bleeding | UO+ L+ CHT |
Young et al., 2012 [40] | 28 | DYG + SCTAT and DYGa | No | 46, XX | Abdominal mass | BO+ O+ CHT+ H |
Esin et al., 2012 [41] | 15 | DYG | No | 46, XX | Irregular vaginal bleeding+ pelvic pain | UO |
Kanagal et al., 2013 [42] | 14 | DYG | No | 46, XX | Abdominal mass | UO+ CHT |
Kulkami et al., 2016 [43] | 20 | DYG | No | Absence of Y in FISH | Abdominal pain | UO |
Gru et al., 2017 [44] | 24 | MGCT (DYG + ST) | No | 46, XX | Incidental finding | UO |
Arafah et al., 2018 [45] | 19 | MGCT (YSC+ COC) | No | 46, XX | Abdominal heaviness+ increased abdominal pain | UO+ O+ CHT |