Skip to main content

Table 1 Comparision of the clinicopathological characteristics between the 220 patients in the NACT-IDS and PDS group with stage IIIC and IV epithelial ovarian cancer

From: Evaluating the benefits of neoadjuvant chemotherapy for advanced epithelial ovarian cancer: a retrospective study

Characteristics

PDS group (n = 141)

NACT group(n = 79)

P value

Age (years), mean ± SD

55.99 ± 11.10

57.08 ± 10.38

0.526

Pathology type

  

0.390

 Serous carcinoma

117(83.0%)

69(87.3%)

 

 Other types

24(17.0%)

10(12.7%)

 

Stage

  

0.123

 IIIC

119(84.4%)

60(75.9%)

 

 IV

22(15.6%)

19(24.1%)

 

Histology grade*

  

0.035

 G1

2(1.4%)

0(0%)

 

 G2

27(19.4%)

6(7.7%)

 

 G3

110(79.1%)

72(92.3%)

 

Initial CA125 level*

  

0.036

 <500 U/ml

60(42.6%)

22(28.2%)

 

  ≥ 500 U/ml

81(57.4%)

56(71.8%)

 

 Pleural effusion

12(8.5%)

14(17.7%)

0.042

 Liver metastasis

15(10.6%)

6(7.6%)

0.461

Tumor distribution

  

< 0.001

 Localized

38(27.0%)

0 (0%)

 

 Diffuse

103(73.0%)

79 (100%)

 

lymphadenectomy

107(75.9%)

60(75.9%)

0.992

Residual disease

  

0.071

 None, R0

46 (32.6%)

34(43.0%)

 

 <1 cm,R1

44 (31.2%)

28(35.4%)

 

  ≥ 1 cm,R2

51 (36.2%)

17(21.5%)

 

 Lymph node metastasis*

69(61.1%)

20(32.3%)

< 0.001

  1. Histology grade* refers to 3 cases with unknown histology grade due to difficult histology recognition
  2. Initial CA125 level* refers to 1 case with unknown Initial CA125 level
  3. Lymph node metastasis* refers to 28 cases in PDS group and 17 cases in NACT group respectively had unknown lymph node accessment as they didn't undergo lymphadenectomy