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Table 1 Clinicpathological parameters associated with AFR in advanced EOC patients

From: Preoperative albumin-to-fibrinogen ratio predicts chemotherapy resistance and prognosis in patients with advanced epithelial ovarian cancer

 

AFR

 

Parameters

Low (≤7.78)

High (> 7.78)

p value

Number

151

162

Age (years)

65.8 ± 8.7

63.1 ± 7.8

0.004*

BMI (kg/m2)

23.1 ± 2.3

23.4 ± 2.1

0.229

Current smokers (n, %)

18 (11.9)

24 (14.8)

0.453

Alcohol (n, %)

14 (9.3)

19 (11.7)

0.479

Comorbidities (n, %)

 Diabetes

22 (14.6)

17 (10.5)

0.275

 Hypertension

27 (17.9)

22 (13.6)

0.295

 Hyperlipemia

15 (9.9)

12 (7.4)

0.426

Histological grade (n, %)

0.042*

 G1

76 (50.3)

100 (61.7)

 G2/3

75 (49.7)

62 (38.3)

Histological type (n, %)

0.444

 Serous

106 (70.2)

120 (74.1)

 Non-serous

45 (29.8)

42 (25.9)

FIGO stage (n, %)

0.032*

 III

113 (74.8)

137 (84.6)

 IV

38 (25.2)

25 (15.4)

ECOG PS (n, %)

0.016*

 0

101 (66.9)

128 (79.0)

  ≥ 1

50 (33.1)

34 (21.0)

Chemotherapy resistance (n, %)

54 (35.8)

40 (24.7)

0.033*

Residual tumor (cm)

0.005*

  ≤ 1

100 (66.2)

130 (80.2)

  > 1

51 (33.8)

32 (19.8)

  1. EOC, Epithelial ovarian cancer; BMI, Body mass index; FIGO, International Federation of Gynecology and Obstetrics; AFR, Albumin-to-fibrinogen ratio; ECOG PS, Eastern cooperative oncology group performance status. P-values were calculated by Student’s t test, Mann–Whitney U test or Chi-squared test. * P < 0.05.