Table 3 Risk factors for PFS by univariate and multiple Cox regression analysis

Age (high vs low)

1.50 (1.11–2.08)

0.016*

1.17 (0.85–1.62)

0.301

BMI (high vs low)

0.82 (0.61–1.15)

0.251

Current smokers (yes vs no)

1.28 (0.97–1.70)

0.112

Alcohol (yes vs no)

1.16 (0.89–1.53)

0.247

Diabetes (yes vs no)

1.03 (0.75–1.41)

0.822

Hypertension (yes vs no)

1.06 (0.73–1.49)

0.794

Hyperlipemia (yes vs no)

0.85 (0.42–1.65)

0.654

Histological grade (G2/3 vs G1)

1.76 (1.19–2.63)

0.012*

1.63 (0.92–2.77)

0.093

Histological type (serous vs non-serous)

1.21 (0.89–1.59)

0.179

FIGO stage (IV vs III)

1.72 (1.09–2.73)

0.024*

1.44 (0.79–2.69)0.254

ECOG PS (≥1 vs 0)

0.86 (0.71–1.07)

0.852

Chemotherapy resistance (yes vs no)

2.07 (1.35–3.17)

0.011*

1.84 (1.12–2.88)

0.032*

Residual tumor (> 1 cm vs ≤1 cm)

2.01 (0.94–4.31)

0.071

1.61 (0.91–2.85)

0.121

Hemoglobin (high vs low)

1.84 (0.69–4.78)

0.211

Platelet (high vs low)

1.55 (0.38–5.78)

0.529

WBC (high vs low)

1.86 (0.86–3.89)

0.127

Albumin (high vs low)

0.92 (0.57–1.42)

0.721

Total protein (high vs low)

0.81 (0.44–1.48)

0.472

Total cholesterol (high vs low)

0.75 (0.47–1.24)

0.261

Triglyceride (high vs low)

1.26 (0.70–2.22)

0.425

CA125 (high vs low)

1.72 (1.22–2.44)

0.011*

1.42 (1.02–2.05)

0.042*

CRP (high vs low)

1.36 (0.69–2.64)

0.373

AFR (≤7.78 vs > 7.78)

1.56 (1.21–2.05)

0.007*

1.38 (1.04–1.82)

0.019*