| Control group (mean ± SD) (n = 120) | PCO patients (mean ± SD) (n = 180) | P |
---|---|---|---|
Age (years) | 31.38 ± 7.88 | 31.95 ± 7.42 | 0.527 |
Systolic blood pressure (mm Hg) | 127.6 ± 5.62 | 131.06 ± 7.021 | <0.001* |
Diastolic blood pressure (mm Hg) | 86.2 ± 3.94 | 87.31 ± 6.074 | 0.076 |
Hirsutism score | 5.53 ± 0.472 | 13.54 ± 2.51 | <0.001* |
Body mass index (kg/m2) | 30.28 ± 57 | 31.889.99 | 0.103 |
Waist/hip ratio | 1.11 ± 0.26 | 1.14 ± 0.30 | 0.392 |
FMI (kg/m2) | 7.66 ± 1.45 | 7.86 ± 1.579 | 0.260 |
FFMI (kg/m2) | 21.81 ± 4.13 | 22.42 ± 4.47 | 0.233 |
Ovarian volume | 4.33 ± 1.1 | 10.64 ± 1.3 | <0.001* |
AFC | 5.33 ± 1.1 | 12.14 ± 1.4 | <0.001* |
Total cholesterol (mg/dL) | 179.47 ± 19.7 | 198.8 ± 52.38 | <0.001* |
Triglycerides (mg/dL) | 150.23 ± 20.84 | 187.6 ± 62.14 | <0.001* |
LDL cholesterol (mg/dL) | 117.48 ± 19.05 | 165.98 ± 60.15 | <0.001* |
HDL cholesterol (mg/dL) | 56.58 ± 6.04 | 39.2 ± 13.63 | <0.001* |
Fasting plasma glucose (mg/dL) | 87.65 ± 9.14 | 108.2 ± 21.62 | <0.001* |
2-h plasma glucose (mg/dL) | 127.6 ± 24.2 | 163.67 ± 41.7 | <0.001* |
HbA1c (%) | 5.82 ± 0.182 | 6.35 ± 0.977 | <0.001* |
Fasting serum insulin (lU/mL) | 7.14 ± 1.427 | 20.05 ± 7.3 | <0.001* |
HOMA-IR | 1.55 ± 0.39 | 4.63 ± 1.87 | <0.001* |
HOMA-β | 169.7 ± 18.14 | 122.01 ± 43.6 | <0.001* |
FSH (mIU/mL) | 6.17 ± 1.53 | 6.6 ± 1.26 | <0.001* |
LH (mIU/mL) | 6.95 ± 0.646 | 10.3 ± 1.23 | <0.001* |
LH/FSH | 1.24 ± 0.54 | 1.6 ± 0.278 | <0.001* |
SHBG (nmol/L) | 53.58 ± 6.04 | 28.8 ± 4.71 | <0.001* |
DHEA-S (mg/mL) | 1.22 ± 0.33 | 2.37 ± 0.316 | <0.001* |
Androstenedione (ng/mL) | 1.41 ± 0.508 | 1.62 ± 0.557 | <0.001* |
Total testosterone (ng/mL) | 0.67 ± 0.18 | 1.1 ± 0.218 | <0.001* |
Free androgen index | 1.03 ± 0.36 | 2.56 ± 1.22 | <0.001* |
hs-CRP (μg/ml) | 2.61 ± 0.51 | 5.56 ± 0.98 | <0.001* |
WBC count (cell×103/μl) | 4.74 ± 0.397 | 6.97 ± 2.31 | <0.001* |
CIMT (mm) | 0.69 ± 0.06 | 1.18 ± 0.46 | <0.001* |
Serum ICAM-1 (ng/ml) | 87.8 ± 49.5 | 445.17 ± 184.95 | <0.001* |
Relative ICAM expression levels | 0.75 ± 0.48 | 4.57 ± 2.16 | <0.001* |