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Table 1 Clinical, anthropometric and laboratory characteristics of studied groups

From: Intercellular adhesion molecule-1 expression and serum levels as markers of pre-clinical atherosclerosis in polycystic ovary syndrome

 

Control group (mean ± SD)

(n = 120)

PCO patients (mean ± SD)

(n = 180)

P

Age (years)

31.38 ± 7.88

31.95 ± 7.42

0.527

Systolic blood pressure (mm Hg)

127.6 ± 5.62

131.06 ± 7.021

<0.001*

Diastolic blood pressure (mm Hg)

86.2 ± 3.94

87.31 ± 6.074

0.076

Hirsutism score

5.53 ± 0.472

13.54 ± 2.51

<0.001*

Body mass index (kg/m2)

30.28 ± 57

31.889.99

0.103

Waist/hip ratio

1.11 ± 0.26

1.14 ± 0.30

0.392

FMI (kg/m2)

7.66 ± 1.45

7.86 ± 1.579

0.260

FFMI (kg/m2)

21.81 ± 4.13

22.42 ± 4.47

0.233

Ovarian volume

4.33 ± 1.1

10.64 ± 1.3

<0.001*

AFC

5.33 ± 1.1

12.14 ± 1.4

<0.001*

Total cholesterol (mg/dL)

179.47 ± 19.7

198.8 ± 52.38

<0.001*

Triglycerides (mg/dL)

150.23 ± 20.84

187.6 ± 62.14

<0.001*

LDL cholesterol (mg/dL)

117.48 ± 19.05

165.98 ± 60.15

<0.001*

HDL cholesterol (mg/dL)

56.58 ± 6.04

39.2 ± 13.63

<0.001*

Fasting plasma glucose (mg/dL)

87.65 ± 9.14

108.2 ± 21.62

<0.001*

2-h plasma glucose (mg/dL)

127.6 ± 24.2

163.67 ± 41.7

<0.001*

HbA1c (%)

5.82 ± 0.182

6.35 ± 0.977

<0.001*

Fasting serum insulin (lU/mL)

7.14 ± 1.427

20.05 ± 7.3

<0.001*

HOMA-IR

1.55 ± 0.39

4.63 ± 1.87

<0.001*

HOMA-β

169.7 ± 18.14

122.01 ± 43.6

<0.001*

FSH (mIU/mL)

6.17 ± 1.53

6.6 ± 1.26

<0.001*

LH (mIU/mL)

6.95 ± 0.646

10.3 ± 1.23

<0.001*

LH/FSH

1.24 ± 0.54

1.6 ± 0.278

<0.001*

SHBG (nmol/L)

53.58 ± 6.04

28.8 ± 4.71

<0.001*

DHEA-S (mg/mL)

1.22 ± 0.33

2.37 ± 0.316

<0.001*

Androstenedione (ng/mL)

1.41 ± 0.508

1.62 ± 0.557

<0.001*

Total testosterone (ng/mL)

0.67 ± 0.18

1.1 ± 0.218

<0.001*

Free androgen index

1.03 ± 0.36

2.56 ± 1.22

<0.001*

hs-CRP (μg/ml)

2.61 ± 0.51

5.56 ± 0.98

<0.001*

WBC count (cell×103/μl)

4.74 ± 0.397

6.97 ± 2.31

<0.001*

CIMT (mm)

0.69 ± 0.06

1.18 ± 0.46

<0.001*

Serum ICAM-1 (ng/ml)

87.8 ± 49.5

445.17 ± 184.95

<0.001*

Relative ICAM expression levels

0.75 ± 0.48

4.57 ± 2.16

<0.001*

  1. FSI fasting serum insulin, FPG fasting plasma glucose, AFC antral follicle cells, FMI fat mass index, FFMI fat free mass index, HOMA-IR homeostasis model assessments of insulin resistance, DHEA dehydroepiandrosterone;. *P < 0.05 when compared with control group