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Table 2 Clinical, anthropometric and laboratory characteristics of PCOS groups

From: Intercellular adhesion molecule-1 expression and serum levels as markers of pre-clinical atherosclerosis in polycystic ovary syndrome

Parameters

PCO patients (n = 180)

NGT Group (mean ± SD)

(n = 75)

IGT Group (mean ± SD)

(n = 65)

T2DM Group (mean ± SD)

(n = 40)

Systolic blood pressure (mm Hg)

127.76 ± 7.21

134.49 ± 4.74a

139.67 ± 7.04b,c

Diastolic blood pressure (mm Hg)

83.8 ± 3.86

87.85 ± 6.33a

90.98 ± 5.80b,c

Hirsutism score

13.78 ± 2.594

13.42 ± 2.9

13.29 ± 1.42

Body mass index (kg/m2)

32.96 ± 14.25

30.11 ± 4.41

32.65 ± 5.73

Waist/hip ratio

0.96 ± 0.212

1.34 ± 0.27a

1.17 ± 0.27b,c

Ovarian volume

9.88 ± 0.491

10.75 ± 1.21a

11.89 ± 1.4b,c

AFC

11.38 ± 0.491

12.25 ± 1.17a

13.39 ± 1.6b,c

FMI (kg/m2)

6.20 ± 0.68

8.7 ± 0.63a

9.49 ± 0.63b,c

FFMI (kg/m2)

17.65 ± 1.96

25.02 ± 1.82a

27.17 ± 1.06b,c

Total cholesterol (mg/dL)

191.21 ± 54.43

201.5 ± 54.43

209.02 ± 43.32

Triglycerides (mg/dL)

174.02 ± 55.3

184.2 ± 57.19

216.04 ± 73.1b,c

LDL cholesterol (mg/dL)

168.15 ± 61.11

163.17 ± 57.96

166.46 ± 63.11

HDL cholesterol (mg/dL)

41.46 ± 11.78

36.21 ± 13.85a

39.8 ± 15.8

FPG (mg/dL)

91.1 ± 6.84

108.16 ± 12.50a

140.5 ± 12.7b,c

2-h blood glucose (mg/dL)

130.28 ± 23.2

171.94 ± 28.68a

212.8 ± 30.1b,c

FSI (lU/mL)

13.5 ± 3.289

26.96 ± 5.51a

21.1 ± 3.34b,c

HOMA-IR

2.85 ± .855

6.25 ± 1.44a

5.34 ± 0.647b,c

HOMA-β

139.23 ± 54.11

124.4 ± 35.3a

108.6 ± 41.55b,c

HbA1c (%)

5.66 ± 0.35

6.37 ± 0.615a

7.62 ± 0.983b,c

Total testosterone (ng/mL)

0.9 ± 0.231

0.99 ± 0.304a

1.07 ± 0.155b,c

Free androgen index

1.813 ± 0.98

2.88 ± 0.81a

3.4 ± 0.69b,c

FSH (mIU/mL)

6.02 ± 1.314

7.107 ± 1.06a

7.05 ± 0.985b

LH (mIU/mL)

9.45 ± 0.491

10.44 ± 1.15a

11.98 ± 0.201b,c

LH/FSH

1.63 ± 0.341

1.48 ± 0.144a

1.73 ± 0.241c

SHBG (nmol/L)

33.54 ± 3.108

26.23 ± 2.011a

24.197 ± 0.96b,c

DHEA-S (mg/mL)

2.17 ± 0.245

2.43 ± 0.241a

2.66 ± 0.286b,c

Androstenedione (ng/mL)

1.23 ± 0.371

1.91 ± 0.539a

1.88 ± 0.43

hs-CRP (μg/ml)

4.92 ± 0.761

5.79 ± 0.760a

6.37 ± 0.91b,c

WBC count (cell×103/μl)

4.79 ± 0.713

8.45 ± 2.27a

8.58 ± 1.281b,c

CIMT (mm)

0.96 ± 0.263

1.09 ± 0.36a

1.74 ± 0.467b,c

Serum ICAM-1 (ng/ml)

281.3 ± 95.29

509.4 ± 82.16a

594.6 ± 156.12b,c

Relative ICAM expression levels

2.68 ± 0.85

5.7 ± 1.52a

6.05 ± 2.119b,c

  1. NGT Normal glucose tolerance, IGT impaired glucose tolerance, T2DM type 2 diabetes mellitus, FSI fasting serum insulin, FPG fasting plasma glucose, AFC antral follicle cells, FMI fat mass index, FFMI fat free mass index, HOMA-IR homeostasis model assessments of insulin resistance, DHEA dehydroepiandrosterone
  2. a significant difference between IGT vs NGT
  3. b significant difference between T2DM vs NGT.,c significant difference between T2DM vs IGT,