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Fig. 2 | Journal of Ovarian Research

Fig. 2

From: Clarithromycin synergizes with cisplatin to inhibit ovarian cancer growth in vitro and in vivo

Fig. 2

DDP combined with CAM synergistically promoted tumors cells apoptosis in C13* and SKOV3 cells. a C13* cells were treated with DDP (80 μM), CAM (20 μM) or both for 48 h, and Annexin V/PI staining was used to detect apoptosis rates. b SKOV3 cells were treated with DDP (40 μM), CAM (10 μM) or both for 48 h, and Annexin V/PI staining was used to detect apoptosis rates. c and d The expressions of cleaved PARP and activated caspase-3 were detected in C13* and SKOV3 cells treated with DDP, CAM or both for 72 h by western blotting analysis, respectively. GAPDH was used as a loading control. Each experiment was performed in triplicate. * P < 0.05

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