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Fig. 3 | Journal of Ovarian Research

Fig. 3

From: The Jun N-terminal kinases signaling pathway plays a “seesaw” role in ovarian carcinoma: a molecular aspect

Fig. 3

JNK signaling pathway mediated drug resistance. a NK signaling pathway mediated by the JNK signaling pathway in ovarian cancer can repair DNA damage through SIRT6/PARP1 or reduce the sensitivity of ovarian cancer tissues to chemotherapy by c-Jun. b Drug resistance mediated by JNK signaling pathway also involves microRNA. MiR-21 inhibits the expression of PDCD4 and promotes resistance, or the interaction between miR-134 and JNK signaling pathway promotes the activation of c-jun/ATF2 and promotes drug resistance

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Journal of Ovarian Research

ISSN: 1757-2215

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