Fig. 1

SOX2 and ST6GAL1 co-amplification. a Aligned TCGA datasets showing copy number alterations for SOX2 (upper panel) and ST6GAL1 (lower panel). Colored circles represent the various types of cancer cohorts. The cohorts were ordered based on the frequency SOX2 amplification in the distinct cohorts and the same cohort order was then used to graph the data for ST6GAL1 copy number variations. Gene amplification is shown in red, deletion in blue. An ovarian serous carcinoma cohort is marked by *. b Aligned individual patient tumors from the ovarian serous carcinoma cohort (*) showing SOX2 and ST6GAL1 co-amplification and co-occurrence. c SOX2 and ST6Gal1 copy number in the NCI-60 series of established cancer cell lines. d SOX2 and ST6Gal1 copy number in the ovarian cancer lines within the NCI-60 panel