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Table 3 Tumor-derived organoids and its applications, adapted from [12, 13, 26, 30]

From: Organoids of epithelial ovarian cancer as an emerging preclinical in vitro tool: a review

Cancer typeAim of study
Breast- Elucidate pathways of tumorigenesis and metastasis
- Detect drug response of organoids
- Validation of disease-causing genomic variations
- Organoid biobank
Colorectal- Genetic diversity of patient- derived tumor organoids and the original tumor biopsy
- Organoid biobank
- Personalized medicine
- Modeling specific subtype of colon cancer
Endometrium- Organoid biobank
- Precision medicine
Glioblastoma- Organoid model of non-epithelial tumor
Liver- Organoid biobank
- Detection of driver mutations
Pancreatic- Pancreatic ductal adenocarcinoma modeling and drug screening
- Organoid model
Prostate- Tumor modeling
- Lineage and cell transition monitoring
RenalMethod for renal carcinoma 3D culture
Stomach and esophageal- Genomic-based classification of gastric cancer
- New driver mutation detection
- Personalized medicine
- Organoid biobank
- Long-term 3D cultures of human gastric stem cells and bacterial infection study