Fig. 5

Volcano plot of detectable genome-wide mRNA profiles in ovarian cancer tissue and normal ovarian tissue samples from GSE14407, GSE18520, and GSE36668, respectively. Blue and red plots represent aberrantly expressed mRNAs with P<0.05 and |log(FC)|>1. Blue plots indicate up-regulated genes, red plots indicate down-regulated genes and green plots indicate normally expressed mRNAs. The x-axis is the fold-change value between the expression of mRNAs in ovarian cancer tissues and normal ovarian tissues. The y-axis is the -log10 of the adj.P.Value for each mRNA, representing the strength of the association. adj.P.Value, adjusted P value; FC, fold change