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Fig. 2 | Journal of Ovarian Research

Fig. 2

From: Withaferin A ameliorates ovarian cancer-induced cachexia and proinflammatory signaling

Fig. 2

Withaferin A ameliorates muscle strength in ovarian cancer-induced cachexia. Quantification of mean (a) forelimb and (b) total limb grip strength normalized to body weight at time of assessment. N = 5 in all groups. (c) Quantification of normalized tibialis anterior (TA), gastrocnemius (GA), and quadriceps femoris (QF) muscle weights to total final body weight. N = 5 (control), 4 (vehicle treated), 5 (WFA 2 mg/kg), and 4 (WFA 6 mg/kg). Opaque black circles indicate individual data points. *P < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001, value significantly different from corresponding value of control mice as determined by one-way ANOVA followed by Tukey’s HSDT. #P < 0.05, value significantly different from corresponding value of vehicle treated group. $P < 0.05, value significantly different from corresponding value of WFA 2 mg/kg group

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