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Table 1 Surface markers used to isolate ovarian cancer stem cells

From: Ovarian cancer stem cells and targeted therapy

Surface marker

The distinctive feature of these cells

References

CD133+

Higher clonogenic and proliferative potentials recapitulate the tumor characteristics in NOD/SCID mice

[33, 34]

CD44+

Targeting CD44 by siRNA induced cell death and decreased the tumor

[35]

CD44+/CD117+

Recapitulate the original tumor in vivo

[33, 36]

CD44+/MyD88+

Presented stem-like characteristics, including constitutive NF-κB activity, high capacity for tumor reconstitution, resistance to chemotherapeutics ability to recapitulate the tumor in vivo and

[37]

CD44+/E-cadherin/CD34

Participate in neovascularization

shorter tumor-free period in vivo and increased

[38]

CD44+/CD24+/EpCAM+

CD44+/CD24

migration and invasion characteristics in vitro

differentiation potential and drug resistance accompanied by higher invasion ability

[39]

[40]