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Table 3 Dichotomous CA125 prediction model in Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO)

From: Development and validation of circulating CA125 prediction models in postmenopausal women

Predictor

Odds Ratio (95% CI)a

Age (per year)

1.04 (1.01–1.07)

Race

 White

Ref

 Non-white

0.68 (0.47–0.99)

Body mass index (kg/m2)

0.95 (0.93–0.97)

Smoking

 Never

Ref

 Current

0.72 (0.31–1.64)

 Former

1.01 (0.78–1.31)

Pack-years among current smokers

1.00 (0.98–1.02)

Pack-years among former smokers

1.01 (1.00–1.01)

Hysterectomy

 No

Ref

 Yes

0.54 (0.41–0.73)

Time since menopause

  < 5 years

Ref

 5–9 years

0.76 (0.52–1.04)

 10–14 years

0.70 (0.46–1.05)

 15–19 years

0.83 (0.52–1.31)

  ≥ 20 years

0.96 (0.56–1.64)

Duration of HT use

 Never users

Ref

  ≤ 1 year

0.60 (0.41–0.87)

 2–3 years

0.80 (0.55–1.15)

 4–5 years

0.88 (0.60–1.29)

 6–9 years

1.27 (0.94–1.71)

  ≥ 10 years

1.22 (0.94–1.58)

AUC

0.64 (0.61–0.66)

  1. aMutually adjusted for all other predictors in this table