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Fig. 2 | Journal of Ovarian Research

Fig. 2

From: S100A10 silencing suppresses proliferation, migration and invasion of ovarian cancer cells and enhances sensitivity to carboplatin

Fig. 2

S100A10 knockdown inhibited cell proliferation and colony formation. (a) Quantitative real-time PCR showing the expression level of S100A10 mRNA in shGFP, shS100A10–1 or shS100A10–2 SKOV3 and A2780 cell lines. (b) Western blots showing the expression of S100A10 protein in shGFP, shS100A10–1 or shS100A10–2 SKOV3 and A2780 cell lines. For quantification, the expression of S100A10 was normalized to that of β-actin. (c) CCK-8 assay showing that the knockdown of S100A10 markedly suppressed the proliferation of SKOV3 and A2780 cells. (d) Colony formation assay demonstrated that S100A10 knockdown decreased colony numbers. Statistical significance was analyzed by ANOVA. Data are expressed as the mean ± standard deviation (n = 3 in each group). * P < 0.05, ** P < 0.01, *** P < 0.001, and **** P < 0.0001 vs. the shGFP group

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