Wnt/β-catenin signalling in ovarian cancer: Insights into its hyperactivation and function in tumorigenesis

Table 2 Wnt/β-catenin pathway-associated long noncoding RNAs in EOC

	Targets	Expression in EOC	Effects on EOC	Effects on β-catenin activity	Reference
Long noncoding RNAs
CCAT2	ND^*	Increased	Promote EMT	Activate	[120]
SNHG20	Inactivate GSK3b	Increased	Promote proliferation and inhibit apoptosis	Activate	[121]
MALAT1	Increase DVL2 and β-catenin	Increased	Promote proliferation, migration and inhibit apoptosis	Activate	[122]
Linc-ROR	ND	Increased	Promote proliferation, migration and invasion through EMT	Activate	[123]
HOTAIR	ND	Increased	Promote proliferation and chemoresistance	Activate	[124]
HOXD-AS1	miR-133a-3p, miR-186-5p	Increased	Promote cell proliferation and invasion	Activate	[113]
circRNAs
Circ-ITCH	miR-145	Decreased	Inhibit OC cells proliferation, migration and invasion	Suppress	[125]
Circ_0061140	miR-370	Increased	Promote cell proliferation and migration	Activate	[109]

ISSN: 1757-2215