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Table 2 Wnt/β-catenin pathway-associated long noncoding RNAs in EOC

From: Wnt/β-catenin signalling in ovarian cancer: Insights into its hyperactivation and function in tumorigenesis

 TargetsExpression in EOCEffects on EOCEffects on β-catenin activityReference
Long noncoding RNAs
CCAT2ND*IncreasedPromote EMTActivate[120]
SNHG20Inactivate GSK3bIncreasedPromote proliferation and inhibit apoptosisActivate[121]
MALAT1Increase DVL2 and β-cateninIncreasedPromote proliferation, migration and inhibit apoptosisActivate[122]
Linc-RORNDIncreasedPromote proliferation, migration and invasion through EMTActivate[123]
HOTAIRNDIncreasedPromote proliferation and chemoresistanceActivate[124]
HOXD-AS1miR-133a-3p,
miR-186-5p
IncreasedPromote cell proliferation and invasionActivate[113]
circRNAs
Circ-ITCHmiR-145DecreasedInhibit OC cells proliferation, migration and invasionSuppress[125]
Circ_0061140miR-370IncreasedPromote cell proliferation and migrationActivate[109]
  1. *ND, not determined