Fig. 3

Concentrations of inflammatory cytokines in follicular fluids

Thirty patients received 12 weeks of Dienogest treatment (2 mg/day) followed by standard controlled ovarian hyperstimulation (COH) for IVF-ET (DNG group). Thirty-four patients received standard COH with mid-luteal phase GnRH agonist down-regulation (control group). The concentrations of inflammatory cytokines, including tumor necrosis factor alpha (TNF-α), interleukin-6 (IL-6), and interleukin-8 (IL-8), were measured in the follicular fluid obtained at the time of oocyte retrieval. Values are the mean ± SD. Statistical analyses were performed with the Mann-Whitney U-test using Bonferroni’s correction.