Table 3 Univariate and multivariate analysis after recurrence

  ≤ 50

1

0.215

1

0.076

1

0.031

 >50

1.553 (0.775–3.114)

2.439 (0.887–6.708)

3.331 (1.116–9.946)

  ≥ 61 m

1

0.014

1

0.004

1

0.321

  < 61 m

2.619 (1.217–5.639)

3.537 (1.503–8.327)

1.657 (0.611–4.492)

 Uni-recur

1

0.508

1

0.388

 Multi-recur

0.751 (0.321–1.755)

1.917 (0.437–8.409)

 Surgery+chemotherapy

1

0.000

1

0.000

1

0.002

1

0.001

 Surgery

4.883 (1.318–18.083)

0.018

10.599 (2.472–45.441)

0.001

2.341 (0.483–11.345)

0.291

2.069 (0.426–10.047)

0.367

 Chemotherapy

15.216 (3.576–64.750)

0.000

15.192 (3.589–64.307)

0.000

9.196 (2.650–31.908)

0.000

13.418 (3.410–52.793)

0.000

Complete resection (N = 34)

N/A

N/A

N/A

N/A

 Yes

1

0.081

1

0.003

 No

2.147 (0.910–5.065)

6.324 (1.860–21.504)

Chemotherapy regimens (N = 31)

N/A

N/A

N/A

N/A

 BEP

1

0.076

1

0.709

 TC/TP/TN/TI

0.675 (0.266–1.714)

0.408

1.037 (0.204–5.264)

0.965

 Other

2.346 (0.795–6.924)

0.123

1.754 (0.390–7.885)

0.464

Cycle (N = 31)

N/A

N/A

N/A

N/A

  ≤ 4

1

0.832

1

0.308

 >4

1.097 (0.467–2.574)

2.241 (0.475–10.570)

Necrosis (N = 22)

N/A

N/A

N/A

N/A

 No

1

0.109

1

0.596

 Yes

2.574 (0.809–8.190)

1.536 (0.315–7.481)

Atypia (N = 22)

N/A

N/A

N/A

N/A

 Mild

1

0.030

1

1.000

 Median

2.676 (0.976–7.337)

0.056

1.000 (0.267–3.742)

1.000

 Severe

19.720 (1.593–244.051)

0.020

1.000 (0.000–12,512.695)

1.000

Mitotic (N = 22)

N/A

N/A

N/A

N/A

  < 5

1

0.334

1

0.308

  > 5

1.639 (0.601–4.470)

2.074 (0.510–8.439)