Outcomes of fertility preservation in women with endometriosis: comparison of progestin-primed ovarian stimulation versus antagonist protocols

Table 3 Simple and multiple linear regression on the number of retrieved oocytes

Variable	Simple linear regression Coefficient 95%CI	p-value	Multiple linear regression Coefficient 95%CI	p-value
Age (years)	−0.23 [− 0.35: −.011]	< 0.001	− 0.48 [− 0.76: − 0.20]	0.001
BMI (kg/m²)	0.35 [− 0.08: 0.15]	0.56
Tobacco use	−0.01 [− 0.02: 0.01]	0.22
Prior pregnancy	0.20 [− 2.3: 2.7]	0.88
Prior surgery for DE	0.52 [− 2.6: 3.7]	0.74
Prior ovarian surgery	− 2.1 [− 4.9: 0.66]	0.13	−2.74 [− 5.28: − 0.20]	0.035
DE (vs. Superficial endometriosis only)	0.1 [− 3.9: 4.1]	0.96
Presence of endometrioma	0.56 [− 2.1: 3.3]	0.68
Presence of adenomyosis	0.44 [− 2.5: 3.4]	0.77
AMH (ng/ml)	1.8 [1.2: 2.4]	< 0.001	1.29 [0.53: 2.05]	0.001
AFC (n)	0.38 [0.19: 0.57]	< 0.001	0.13 [− 0.09: 0.34]	0.248

BMI Body Mass Index, DE Deep Endometriosis, AMH Anti-Müllerian Hormone, AFC Antral Follicular Count; Tested variables in the simple linear regression model included: body mass index, tobacco consumption, gravidity, parity, history of surgery for DE, presence of DE (vs. superficial endometriosis only), presence of adenomyosis, presence of endometrioma, size of the biggest endometrioma, cumulative size of the endometriomas, long-term oral progestin treatment, PPOS protocol (vs. antagonist protocol)

ISSN: 1757-2215